Anmol Pitliya, M.D.
Predictors of Device Related Thrombosis After Transcatheter Left Atrial Appendage Occlusion
In a recent study published in Circulation: Cardiovascular Interventions, Pracon et al. suggested that the incidence of device related thrombosis (DRT) among patients undergoing percutaneous left atrial appendage occlusion is related to patient (history of thromboembolic events and lower left ventricular ejection fraction) and procedural (deep implantation and larger occluder size) characteristics.
Immune Checkpoint Inhibitors-associated Myocarditis
In a recently published study in the Journal of American College of Cardiology, it was suggested that myocarditis following administration of immune checkpoint inhibitors (ICI) for various cancers is underestimated. Myocarditis occurs early in the course of treatment (~ 30 days), with the majority of cases presenting within 3 months of initiation of therapy. ICI-associated myocarditis responded to high doses (1000 mg) of steroids.
