Pre-PCI Impella Device Improves Outcome in Acute MI complicated by Cardiogenic Shock (AMICS)

A non-randomized study published in the American Heart Journal showed increased survival rates in patients with Impella device being used as the first support strategy for patients with acute myocardial infarction complicated by cardiogenic shock (AMICS) when invasive hemodynamic monitoring was used, and at centers with higher Impella implantation volume. Continue reading

Tafamidis, A Real Hope for People with Transthyretin Cardiomyopathy?

On Thursday, March 29th, Pfizer announced positive topline results from ATTR-ACT trial of tafamidis in patients with transthyretin cardiomyopathy. According to Pfizer, “Tafamidis met its primary endpoint, demonstrating a statistically significant reduction in the composite of all-cause mortality and frequency of cardiovascular-related hospitalizations compared to placebo at 30 months. The preliminary safety data showed that tafamidis was generally well tolerated in this population and no new safety signals were identified”. Continue reading

Association of High-Sensitivity Cardiac Troponins (hs-cTn) and the Risk of New-onset Heart Failure

A recent study, published in the Journal of American College of Cardiology, concluded that there is a strong association of high sensitivity cardiac troponin (hs-cTn) with the risk of new-onset heart failure (HF), independent of population at risk, cardiovascular risk factors, and natriuretic peptide levels. Continue reading

ICON RELOADED: A New Future for NT-proBNP

A multicenter, international, North American study published in the Journal of the American College of Cardiology has indicated that N-terminal pro–B-type natriuretic peptide (NT-proBNP) testing may be valuable in the identification or exclusion of heart failure in emergency department patients with shortness of breath.

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HeartMate 3: Magnetic Pump in Advanced Heart Failure

According to a new study published in the New England Journal of Medicine, a fully magnetically levitated centrifugal- flow pump has been found to be superior to a mechanical-bearing axial-flow pump in advanced heart failure patients in terms of survival free of disabling stroke or reoperation for removal in case of device malfunction.

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MOMENTUM III: HeartMate III demonstrated 2-year Survival Benefit Compared to HeartMate II

Dr. Mehra and Dr. Gibson Discuss

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MOMENTUM III: HeartMate III demonstrated 2-year Survival Benefit Compared to HeartMate II Dr. Mehra and Dr. Gibson Discuss

ARISTOTLE: Digoxin in AFib with and without heart failure Dr. Renato Lopes and Dr. C. Michael Gibson Discuss

Silent MI: A Risk Factor for Heart Failure? Link between silent myocardial infarction and heart failure

In a recent analysis published in the Journal of the American College of Cardiology, a link between silent myocardial infarction and subsequent heart failure has been demonstrated, revealing a novel potential marker for heart failure. Continue reading

Transcatheter Inter-atrial Shunt Device for Treatment of HF

Dr. C. Michael Gibson discusses the trial findings with Dr. Sanjiv Shah at AHA 2017.

Transcatheter Inter-atrial Shunt Device for Treatment of HF Dr. Sanjiv Shah and Dr. C. Michael Gibson Discuss REDUCE LAP-HF