Acute Coronary Syndrome
Using High Sensitivity Troponin T in Ruling Out Acute Coronary Syndrome
High sensitivity troponin T (hsTnT) can be a reliable tool for excluding acute coronary syndrome (ACS) in very low-risk patients, according to a recent study published in the Journal of American Medical Association. Continue reading
ODYSSEY Demonstrates a Mortality Benefit in ACS Patients
Results of the much anticipated ODYSSEY Outcomes trial were presented today by Professor Phillipe Gabriel Steg, who is the chief of cardiology at Bichat-Claude Bernard Hospital, at the American College of Cardiology (ACC) Scientific Sessions in Orlando. Alirocumab, a monoclonal antibody directed against PCSK9, reduced major adverse cardiovascular events (MACE), myocardial infarction (MI), ischemic stroke and all-cause mortality in patients post-acute coronary syndrome (ACS), who were on high-intensity statin therapy. Continue reading
AHA Releases a Scientific Statement for Spontaneous Coronary Artery Dissection
Spontaneous coronary artery dissection (SCAD) has gained considerable recognition as an important cause of acute myocardial infarction (AMI), particularly among young females without conventional cardiovascular risk factors. To facilitate dissemination of current knowledge on SCAD, a Scientific Statement from the American Heart Association was recently published in Circulation by Hayes et al. concerning the current knowledge of epidemiology, precipitants and triggers, pathophysiology, and associated comorbidities. Furthermore, the document provides an overview of the advance in diagnostic imaging, management options, as well as the prognostic outlook for SCAD, in hopes of spurring a paradigm shift in the care of this under-diagnosed condition. Continue reading
Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection
In a recent retrospective cohort study published in the New England Journal Medicine, a significant association was found between acute respiratory infections, particularly influenza, and the occurrence of acute myocardial infarction (MI) in the following week. The study also highlights the increased risk in older patients and in those who are hospitalized for the first time for an MI. Continue reading
D-dimer Level is Associated With Increased Long-term Cancer Incidence and All-cause Mortality
According to a recently published article in Circulation, it was found that D-dimer level is an independent predictor of the long-term (up to 16 years) risk of arterial and venous events, cause-specific mortality, and the incidence of new cancers. The results of the study are based on a subanalysis of the LIPID trial. Continue reading
Anticipating ODYSSEY Outcomes
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