Medications acting on the renin-angiotensin-aldosterone system (RAAS), such as ACE inhibitors and angiotensin receptor blockers, did not increase the likelihood of a positive test for Covid-19 or the severity of the Covid-19. A cohort study of more than 12,500 patients conducted in a large health network in New York City, led by Dr. Reynolds, revealed. The findings of the study were recently published in the New England Journal of Medicine. Continue reading
The positive effect of the remote patient management (RPM) intervention on morbidity and mortality, seen in the Telemedical Interventional Management in Heart Failure II (TIM-HF2) trial was no longer observed 1 year after stopping the RPM intervention. The extended follow-up results of the TIM-HF2 trial led by Dr. Koehler (Department of Cardiology and Angiology, Centre for Cardiovascular Telemedicine, Charité–Universitätsmedizin Berlin, Berlin, Germany) was recently published in the Lancet. Continue reading
In a large population-based study, a significant and sustained survival benefit was observed in patients with out-of-hospital cardiac arrest treated at teaching hospitals. The report of the study led by Dr. Czarnecki was recently published in Circulation: Cardiovascular Quality and Outcomes. Continue reading
In an autopsy-based, histopathological analysis of stented coronary lesions, severe calcification was an independent risk factor for delayed strut coverage and healing after newer-generation DES. The report of the study led by Torri was recently published in the European Heart Journal.
One in eight patients with atherosclerotic cardiovascular disease reports medication nonadherence due to cost, according to a nationally representative survey of more than 14,000 US adults. The findings of the study led by Dr. Rohan Khera (University of Texas Southwestern Medical Center, Dallas, US) was recently published in Circulation.
The result of a study, presented at ACC 2019 in March, 2019 and recently published in JACC Interventional Cardiology, showed that despite angiographically successful percutaneous coronary intervention (PCI), physiological assessment detected residual ischemia in 1 out of 4 patients after coronary stenting. The majority of the cases were due to inappropriate focal lesions which seem amenable to treatment with additional PCI.
Use of ticagrelor plus aspirin in patients with stable coronary artery disease and type 2 diabetes significantly lowers the risk of major adverse cardiovascular events compared with aspirin alone, but at the cost of higher major bleeding, according to the THEMIS study. The results were presented at ESC 2019 and published in the New England Journal of Medicine.
The results of a substudy of the COMPLETE Trial were presented at TCT 2019 by Dr. David Wood, an interventional cardiologist, and Professor of Medicine at the University of British Columbia, Canada. The analyses revealed that compared with culprit-lesion only PCI, the timing of complete revascularization, whether performed early during the index hospitalization or after discharge have similar benefits on major cardiovascular events.
In a meta-analysis of RCTs comparing TAVR (Transcatheter Aortic Valve Replacement) versus SAVR (Surgical Aortic Valve Replacement) in low-risk patients with severe AS, TAVR was associated with a significantly lower risk of all-cause and cardiovascular mortality at 1 year follow up. The study conducted by Kolte et.al was recently published in the Journal of American College of Cardiology.
Data from CLIMA registry shows that simultaneous presence of four optical coherence tomography (OCT) plaque vulnerability features are associated with a seven-fold increased risk of future major coronary events. The study, led by Prati et al., is recently published in the European Heart Journal.
Murai et al. devised a novel physiology-based method of estimating the amount of myocardium subtended by coronary stenosis, which is feasible and can be performed in the catheterization laboratory with a Doppler sensor-equipped guidewire. The study was published in the recent issue of Circulation: Cardiovascular Interventions.
Anti-inflammatory biologic therapy used for the treatment of moderate to severe psoriasis is associated with reduced coronary inflammation in patients with the skin condition. The recent study by Elnabawi et al., published in the Journal of the American Medical Association (JAMA) Cardiology, revealed.
Compared with optical coherence tomography (OCT), fractional flow reserve (FFR) was associated with a higher percentage of medical therapy, lower risk of acute kidney injury, shorter hospital stay, and reduced costs at one month among patients with intermediate coronary lesions. The study by Leone et al., recently published in the Journal of American Heart Association, revealed.
Among patients hospitalized for an acute coronary syndrome (ACS), adding ezetimibe to simvastatin further reduced the risk of cardiovascular events, and the benefit was ten times greater in the elderly than younger individuals. A secondary analysis of the IMPROVE-IT trial, published in JAMA Cardiology, revealed.
Among individuals who had sudden cardiac death (SCD) due to ischemic cardiac disease, a substantial number had a previously undetected myocardial infarction at autopsy; some of them had electrocardiographic abnormalities prior to the death. The study by Vähätalo et al., published in JAMA Cardiology, revealed.