Month: June 2019
RM-ALONE: Trial Demonstrates A More Efficient and Simpler Follow Up Protocol For Patients with Implantable Cardiac Defibrillators and Pacemakers
A randomized trial led by Dr. Francisco Javier Garcia-Fernandez, published in the European Heart Journal, demonstrated that a simplified protocol of remote monitoring and for monitoring patients with implantable cardiac defibrillators or pacemakers was as safe and efficient as a protocol involving in-patient follow up.
PROMISE Trial: High-Sensitivity Troponins May Assist in Detecting Obstructive CAD in Symptomatic Outpatients
Increasing concentrations of hsTnI are significantly associated with the presence and severity of coronary artery disease (CAD) among stable outpatients with chest pain, an analysis of PROMISE trial indicates. The study, conducted by Prof. James Januzzi et al., is recently published in the June 1, 2019, issue of the Journal of the American College of Cardiology: Cardiovascular Imaging.
MR-INFORM: Myocardial Perfusion Based Strategy to Determine Need for Revascularization Shown to be Non-Inferior to Invasive Angiography in Reducing the Occurrence of Major Adverse Cardiovascular Events in Patients with Stable Angina
A trial led by Dr. Eike Nagel published in the New England Journal of Medicine showed that among patients with stable angina and risk factors for coronary artery disease, a myocardial-perfusion cardiovascular MRI based strategy to determine eligibility for revascularization was associated with a lower incidence of coronary revascularization than invasive angiography with fractional flow reserve (FFR) and was non-inferior to FFR in terms of the occurrence of major adverse cardiovascular outcomes.
CREOLE: Amlodipine with Either Perindopril or Hydrochlorothiazide Is Better Than Perindopril and Hydrochlorothiazide in Reducing Blood Pressure In Black Patients in Sub-Saharan Africa
A trial led by Dr. Dike Ojji published in the New England Journal of Medicine showed that in black patients in sub-Saharan Africa, amlodipine plus either hydrochlorothiazide or perindopril was more effective than perindopril plus hydrochlorothiazide at lowering blood pressure at 6 months.
Study Shows Noninvasive Hemodynamic Assessment Can Potentially Be Used To Identify Lesions At Risk of Progressing to Acute Coronary Syndrome
A study led by Dr. Joo Myung Lee showed that noninvasive hemodynamic assessment can be used to enhance the identification of high-risk plaques that could subsequently cause acute coronary syndrome (ACS). The study published in JACC: Cardiovascular Imaging suggests that noninvasive hemodynamic assessment could be integrated into the current standard of practice to potentially improve identification of a culprit lesion in future ACS.
TREAT Trial: No Difference in Recurrent Cardiovascular Events by 1 Year Between Ticagrelor and Clopidogrel in Patients with a STEMI Who Receive Fibrinolysis
A randomized controlled trial led by Dr. Otavio Berwanger published in JACC showed that in patients less than 75 with an ST-elevation myocardial infarction, administering ticagrelor as opposed to clopidogrel does not offer a reduced rate of recurrent cardiovascular events.
Simulation Models Suggest Using Combination Drugs Is More Cost Effective Than Current Standard of Care in Patients with Cardiovascular Disease
Using microsimulation models, Dr. Thomas Gaziano showed that the use of a polypill has a favorable cost profile for secondary cardiovascular disease prevention in the United States. The findings of the study published in the American Heart Journal suggest that a polypill would be economically advantageous for both the patients and the payers.
New Study Demonstrates Significant Burden of New Onset Atrial Fibrillation in Patients Undergoing Aortic Valve Replacement
A study led by Dr. Rajat Kalra published in JAMA Internal Medicine showed that new-onset atrial fibrillation is a significant burden on patients after aortic valve replacement either through trans-jugular aortic valve implantation (TAVI) or aortic valve replacement (AVR). Additionally, the investigators demonstrated that atrial fibrillation (AF) was higher after AVR than after TAVI.
Latest Cross-Sectional Study Links Dietary Pattern Specific Protein Biomarkers to Development of Cardiovascular Disease
According to a nationwide cross-sectional study, protein biomarkers along with specific dietary patterns are linked to the development of cardiovascular disease (CVD). These findings, published in the Journal of the American Heart Association, suggest associations between dietary patterns and protein biomarkers have a role in the pathways related to inflammation, endothelial and immune function, cell adhesion and metabolism. Over the years, the role of diet in the prevention of CVD has been scientifically proven; unhealthy dietary components are important risk factors for the total global burden of this comorbidity. Continue reading
New 15,000 Patient Study In Young Adult Demonstrates Increased Mortality For Up To 15 Years After Stroke
A study led by Dr. Merel Sanne Ekker demonstrated that when compared to the general population, patients between the age of 18 and 49 who had a stroke and survived the first 30 days were at a higher risk of mortality up to 15 years in the future.
New Study Suggests That Non-Fasting Lipid Levels May Be Used Instead of Fasting Lipid Levels in Cardiovascular Disease Risk Screening and Treatment
In a study published in JAMA Internal Medicine showed that both fasting and non-fasting lipid levels were associated with incident coronary and atherosclerotic cardiovascular disease (ASCVD) risk and yielded similar results. The study led by Dr. Samia Mora suggests that routine measurement of non-fasting lipid levels may help in ASCVD risk screening and treatment.
Genetic Study Shows LPA Associated with Calcific Aortic Valve Stenosis and Increased Aortic Valve Microcalcification in First Degree Relatives
A study led by Nicolas Perrot published in JAMA Cardiology showed that a genetically elevated lipoprotein A (LPA) levels was associated with an increased risk of calcific aortic valve stenosis (CAVS). The evidence presented in this study supports the use of LPA screening for calcific aortic valve stenosis.
New Study Finds Higher Rates of All-Cause, Cardiovascular and Neurodegenerative Mortality in NFL Players when Compared to MLB Players
A study led by Vy Nguyen published in JAMA Network Open showed that when compared to Major League Baseball (MLB) players, US National Football League (NFL) players had higher all-cause, cardiovascular, and neurodegenerative mortality rates.
