Randomized Trial Shows That Transcatheter Aortic-valve Replacement is Non-inferior to Surgery in Low Risk Patients
A study by Dr. Jeffrey Popma and colleagues published in the New…
Transcranial Ultrasound Used As an Adjunct to tPA Fails To Improve Functionality in Ischemic Stroke Patients
A randomized, mutilcenter, placebo-controlled, phase 3 clinical trial which enrolled 676 patients…
STOPDAPT-2 Explores Safety and Efficacy of 1-month DAPT Followed by Clopidogrel Monotherapy vs Standard 12-month DAPT After Drug-Eluting Stent Implantation
The results of the STOP-DAPT 2 randomized controlled trial were presented by…
Dapagliflozin and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Prior MI
According to a presentation by Dr. Marc P. Bonaca at the American…
TAVR Using Balloon Expandable Valve Superior To Surgical Aortic Valve Replacement In Low Risk Patients With Severe Aortic Valve Stenosis
A randomized multi-center trial which enrolled 1000 patients from 71 centers around…
TREAT Trial Addresses the Safety and Efficacy of Ticagrelor Use for STEMI Management in the Setting of Fibrinolytic Therapy
According to the results of the TREAT trial, among patients aged under…
Total Event Analysis from REDUCE-IT Showcases a Substantial Reduction in the Burden of Ischemic Events, Experts Debate Possible Mechanisms of Action of Icosapent Ethyl
The total event analysis from the REDUCE-IT trial, presented at ACC 2019…
AUGUSTUS: Less Bleeding and Fewer Hospitalizations Without Significant Differences in Ischemic Events With Apixaban and No Aspirin in Patients With AFib and ACS
ACC 2019: In patients with atrial fibrillation and a recent acute coronary…
HeartMate3 Found to be More Superior Than Other LVADs on Endpoints of Stroke, Pump Thrombosis and Bleeding Complications
The largest LVAD trial ever to be performed, led by Dr. Mandeep…
COAPT Analysis Affirms Quality of Life Advantage of MitraClip for Secondary MR
NEW ORLEANS -- Transcatheter repair of functional mitral regurgitation (or secondary MR)…
HEARTLINE: A 180,000 Patient-Strong, Pragmatic, Real World Randomized Trial Assesses the Prowess of Apple Technology in Afib Diagnosis and Improvement of Hard Outcomes
The design of the HEARTLINE randomized trial of up to 180,000 pts…
Findings From a Randomized Controlled Trial May Usher the Adoption of Angiotensin–Neprilysin Inhibition to the Heart-Failure Armamentarium
The results of a trial presented by Dr. Adam DeVore at the…
Is the Improvement in Fractional Flow Reserve After Percutaneous Coronary Intervention (ΔFFR) Associated With Clinical Outcome and Symptomatic Relief?
In an analysis of two randomized clinical trials published in JAMA cardiology,…
ALERTS: Use of an Implanted Electrocardiographic Monitoring Device in High-Risk Patients Aids in the Early Detection of ACS
According to a randomized controlled trial led by Dr. Michael Gibson, PERFUSE…
DECISION-CTO Demonstrates No Significant Difference in Death, MI, Stroke, or Any Revascularization with CTO PCI vs. No CTO PCI
The results of the DECISION-CTO trial conducted by Lee et al. showcased…
Anti-Inflammatory Therapy May Not Prevent Atherosclerotic Events
A randomized double-blinded trial called Cardiovascular Inflammation Reduction Trial (CIRT) recently published…
Early Switch from Intravenous to Oral Antibiotic Therapy for Left-Sided Endocarditis
Among patients who had left-sided infective endocarditis (IE) caused by common bacteria,…
Randomized Trial Comparing Bilateral with Single Internal-Thoracic-Artery Grafting for CABG Shows No Significant Difference in All-Cause Mortality
A recent study published in the New England Journal of Medicine showed…
Adjunctive Low Dose Alteplase During Primary PCI Fails to Imrpove Microvascular Obstruction in STEMI Patients
A multi-center randomized, double blind, placebo-controlled, parallel group clinical trial has shown…
2018: Cardiology News at A Glance
COAPT trial This prospective, multicenter, open-label, randomized trial aimed to assess the…