IVUS-Guided DES Reduced MACE at 1 year Compared to Angiography-Guided PCI: IVUS-ACS Trial
Key Points: The IVUS-ACS trial assessed whether the use of intravascular ultrasound…
IVUS -DBC: IVUS-guided drug-coated balloon angioplasty improves primary patency
Key Points: One-year success rates of angioplasty in peripheral artery disease (PAD)…
A technology assisted Web App allowed >90% of consumers to correctly self-select for statin use and achieve clinically important LDL-C reduction
Key Points: Nonprescription statin access may help statin-eligible patients receive appropriate treatment.…
PROACT: Enalapril Does Not Mitigate Anthracycline Toxicity in Breast Cancer and NHL
Key Points: Anthracycline toxicity is an important cause of cardiomyopathy; it is…
Topical TXA Does Not Reduce Peri-Operative Seizures but Increases Risk of Transfusion in Cardiac Surgery Compared to Intravenous TXA
Key Points: IV TXA is used to prevent peri-operative bleeding in cardiac…
IMPROVE-HCM: Cardiac Mitotrope -Ninerafaxstat- Improves Functional Capacity in Symptomatic Non-Obstructive HCM
Key Points: Despite the high symptomatic burden, very few effective treatments exits…
A Restrictive Benzodiazepine Strategy During Cardiac Surgery Does Not Reduce Post-Operative Delirium
Key Points: Benzodiazepine use contributes to delirium before and after cardiac surgery,…
TRAVERSE: Transseptal approach to LV ablation results in fewer cerebral emboli compared to retrograde aortic approach
Key Points: Among patients who undergo endocardial ablation for left ventricular arrythmias,…
FFR-Guided Complete Revascularization in STEMI did not reduce MACE vs Culprit-lesion only PCI: The FULL REVASC Trial
Key Points Researchers compared outcomes in patients with STEMI or very-high-risk non-STEMI…
PREVENT: PCI of non-flow-limiting vulnerable plaques reduced MACE compared to medical therapy alone
Key Points: Vulnerable plaques can lead to acute coronary syndromes, but it…
PERFORM-TAVR: Home based exercise and protein supplementation improves physical performance in frail adults post-TAVR
Key Points: Many frail patients experience poor physical performance after TAVR, even…
EMBO-ABL: Cryoballoon non-inferior to radiofrequency catheter ablation for AF for silent cerebral events
Key Points: Among AF patients undergoing catheter ablation, cryoballoon was non-inferior compared…
RELIEVE HF: Inter-Atrial Shunting Does Not Reduce Symptoms or Improve Prognosis in HF
Key Points: Inter-atrial shunting (IAS) may provide a useful opportunity to dynamically…
SHASTA 2: Novel RNAi Therapeutic Plozasiran Results in Sustained Reduction In Triglycerides in Severe Hypertriglyceridemia
Key Points: Severe hypertriglyceridemia portends high risk of both CVD and acute…
DanGer Shock: Impella Reduces All-Cause Mortality in STEMI Cardiogenic Shock
Key Points: Cardiogenic shock (CS) mortality remains high despite increased utilization of…
AT-001, a potent aldose reductase inhibitor, did not improve exercise capacity in diabetic cardiomyopathy with impaired exercise capacity
Key Points: The ARISE-HF trial evaluates the use of AT-001, a potent…
TAVR non-inferior to SAVR in Low to Intermediate Risk Patients With Severe Aortic Stenosis: DEDICATE-DZHK6 Trial
Key Points In the DEDICATE-DZHK6 trial, patients with a history of severe…
ORBITA COSMIC: Coronary sinus reducer did not improve transmural myocardial perfusion but angina symptoms
Key Points - Coronary sinus reduction (CSR) is a potential therapeutic device…
TARGET BP I: Alcohol-mediated renal artery denervation reduced SBP in treatment-resistant hypertension at 3 months compared to sham control
Key Points: Achieving hypertension control has remained an elusive goal in the…
Hózhó: Phone-based GDMT Initiation and Uptitration Feasible and Effective among HFrEF patients in Navajo Nation
Key Points: GDMT utilization is suboptimal among American Indian patients with HFrEF…