ApoA-I Infusions and Burden of Ischemic Events after Acute Myocardial Infarction
KEY POINTS: In this prespecified exploratory analysis of the AEGIS-II trial, the…
Apolipoprotein A-I infusions Lowers Risk of Recurrent CV Events in Patients With Baseline LDL-C ≥100 mg/dL
KEY POINTS: In this exploratory analysis of the AEGIS-II randomized control trial,…
Improved Accuracy of HF Diagnosis with HFDetect-AI
Key Points: HFDetect-AI significantly improves the accuracy of diagnosing heart failure by…
Pre-Hospital Pulse-Dose Glucocorticoid Did not Reduce Infarct Size in STEMI: PULSE-MI
Key Points: The PULSE-MI trial assessed the effects of pre-hospital pulse-dose glucocorticoid…
ECLS-SHOCK: At One Year, ECMO Does Not Reduce Mortality in Acute MI-Related Cardiogenic Shock
Key Points: The 30-day ECLS SHOCK study demonstrated no benefit to up-front…
REC-CAGEFREE I: Drug Coated Balloon Fails To Achieve Non-Inferiority vs DES For De Novo Coronary Lesions
Key Points Drug-eluting stents are the standard of care for percutaneous coronary…
Plozasiran Lowered Triglyceride Levels and Pancreatitis in Persistent Chylomicronemia: PALISADE
Key Points: Familial chylomicronemia syndrome (FCS) is a clinically or genetically defined…
Bailout GP IIb/IIIa inhibition in AMI with angiographic MVO failed to reduce the primary endpoint infarct size but decreased CMR-derived MVO: The REVERSE-FLOW trial
Key Points: Though primary PCI for coronary obstruction is first-line therapy in…
AZALEA-TIMI 71 Sub-study: Periprocedural Bleeding Risk Very Low and Similar With Long-acting Factor XI Inhibitor Abelacimab vs Rivaroxaban
Key Points: Factor XI inhibitors have the potential to reduce thromboembolic events…
De-escalation to Ticagrelor Monotherapy Beneficial in Ischemic Events and Bleeding vs 12 months of DAPT: a Systematic Review and Individual Patient-Level Meta-analysis
KEY POINTS: Ticagrelor monotherapy was found to be non-inferior to 12 months…
Microvascular Resistance Reserve as a Potential Predictor of Angina in Moderate Coronary Stenoses.
Key Points: The Microvascular Resistance Reserve (MRR), a novel measurement, assess the…
Functional Improvement of non-infarcT relaTed coronary artery stenosis by Extensive LDL-C Reduction with a PCSK9 Antibody (FITTER)
Key Points: Adverse cardiovascular events can still occur from atherosclerotic events in…
A Low-Dose Triple Single-Pill Combination Effective at Lowering Blood Pressure
Key Points: A single pill containing low doses of three different medicines…
OCCUPI: Optical Coherence Tomography (OCT) Outperforms Conventional Angiography in Guiding Revascularization for Complex Coronary Lesions
Key Points: In all-comer populations, coronary imaging guidance shows superior outcomes compared…
EARTH STEMI: Complete Revascularization Reduces Ischemic Events up to 4 years Among Older Patients with STEMI with Multivessel Disease
Key Points: Approximately 50% of patients with STEMI have multivessel disease but…
SENIOR-RITA: In Elderly Patients With NSTEMI, An Invasive Strategy Improved Clinical Outcomes Compared To Optimal Medical Therapy Alone
Key Points: Many older patients with NSTEMI do not receive coronary angiography…
Safety and care of no fasting prior to catheterization laboratory procedures: a non-inferiority randomized control trial protocol (SCOFF trial)
KEY POINTS: Fasting before cardiac catheterization is a common practice, however, the…
FINEARTS-HF – Finerenone Improves outcomes in in HF with mildly reduced and preserved ejection fraction
KEY POINTS: There is a scarcity of treatments for HFpEF and HFmrEF…
GUARD–AF: Wearable ECG Patch Increased the Yield of AF Diagnosis
Key Points: A 14-day heart rhythm monitoring with a wearable patch in…
OCEANIC AF – Asundexian is inferior to apixaban for stroke prevention in patients with atrial fibrillation
Key Points: Factor XIa inhibition may reduce stroke risk while causing bleeding.…