EPIC-STEMI: Early Routine PCSK-9 Use Added to High Intensity Statin Reduces LDL after Primary PCI for STEMI
Key Points: Early high-intensity statin therapy is standard of practice in acute…
TIPS-3 Trial: The Combination of Polypill and Aspirin Administered to Patients at Intermediate Risk Led to a Lower Incidence of Cardiovascular Events Compared With Double Placebo
A recent trial by Dr. Salim Yusuf, published in The New England Journal…
REPLACE COVID Trial: Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers Can Be Safely Continued in Patients Admitted to Hospital With COVID-19
A recent trial by Dr. Jordana B Cohen, published in The LANCET, indicated that…
DAPA Trial: Prophylactic Defibrillator Implantation After Primary Percutaneous Coronary Intervention Lowers Long Term Mortality in Patients at High Risk of Death
Results of the DAPA trial, published in Circulation: Arrhythmia and Electrophysiology, demonstrated…
COACT Trial Shows Immediate Coronary Angiography Does Not Change the 1-Year Clinical Outcomes of Patients After Cardiac Arrest Without ST-Segment Elevation
A trial by Dr. Jorrit S. Lemkes, published in JAMA Cardiology, demonstrated…
PREMIER Trial Shows Incremental Plaque Regression by a Single Lipid Apheresis and Maintained Statin Therapy in ACS Patients Treated With PCI
A recent study by Dr. Banerjee, published in Circulation: Cardiovascular Interventions, demonstrated…
Post Hoc Analyses of GLOBAL LEADERS Trial: Compared with Standard 12-Month Dual Anti-Platelet Therapy, Ticagrelor Monotherapy Reduced the Ischemic and Bleeding Events by up to 8% Following Percutaneous Coronary Intervention
The post hoc analyses of GLOBAL LEADERS study by Dr. Hara, published…
100,000 Patient Meta-Analysis Shows Carotid Intima-Media Thickness Progression Can Be Used as a Surrogate Marker for Cardiovascular Risk
A recent meta-analysis of clinical trials with more than 100,000 patients has…
SASSICAIA Trial Showed No Difference Between Intensified Prasugrel-Based and Standard Clopidogrel-Based Loading Strategies in Terms of Safety and Efficacy in Patients Undergoing Elective Percutaneous Coronary Intervention
A recent study by Dr. Julinda Mehilli, M.D., published in Circulation journal,…
A Population-Based Study Showed No Association Between COVID-19-Induced In-Hospital Death and Angiotensin-Converting–Enzyme Inhibitors and Angiotensin-Receptor Blockers Use
A recent study by Dr. Mehra, published in the New England Journal…
ORION-10 and ORION-11: Pooled Analysis of Two Phase 3 Trials Showed Sustained LDL Cholesterol Reduction with Inclisiran in Patients with ASCVD or ASCVD Risk Equivalent
The results of a pooled analysis of the ORION-10 and ORION-11 trials…
Study Shows Patient Self Reports Overestimated And Pharmacy Fills Underestimated Medication Persistence
In an original investigation done by Dr. Alexander C. Fanaroff et al and…
1K Plaque Associated With Lower Future ACS Risk: Case Control Cohort Study (Analysis from ICONIC Study)
In an original investigation by Dr. Alexander R. van Rosendael et al…
Study Shows Pre-Dilation Associated with Worse Outcomes As Compared to Direct Stenting of Saphenous Vein Graft Lesions in Patients Undergoing PCI
A post-hoc analysis of the Drug-Eluting Stents Versus Bare-Metal Stents in Saphenous…
Randomized Trial Shows Prasugrel Associated with Better Endothelial Function and Stronger Platelet Inhibition as Compared to Clopidogrel or Ticagrelor in Patients with ACS Who Undergo Stenting
In a recent randomized, three-arm, parallel, blinded study by Dr. Schnorbus, published…
Persistently Elevated Neuropeptide Y, a Sympathetic Neurotransmitter, is Found to be Associated with Ventricular Arrhythmias in Patients with Myocardial Infarction
The sympathetic drive leading to the release of arrhythmogenic agents after myocardial…
385,000 Patient Study Shows Poor Sleep Behavior Associated With Increased Risk of Coronary Heart Disease and Stroke
A study led by Dr. Mengyu Fan published in the European Heart…
Lower Levels of Circulating Progenitor Cells Associated with Increased Risk of Myocardial Infarction and Death In Patients with Stable Coronary Artery Disease
In patients with stable coronary artery disease, a decrease in circulating progenitor…
Study Suggests Coronary Microvascular Dysfunction and Not Glomerular Filtration Rate Associated with Abnormal Cardiac Mechanics and Worse Clinical Outcomes in Patients with Chronic Kidney Disease
A study led by Dr. Navakaranbir Bajaj published in Circulation showed that…
COMPLETE Trial OCT Substudy: Non-Culprit Lesions with Vulnerable Plaque Morphology Found In Half of Patients with STEMI and Multivessel Disease
The results of the COMPLETE Optical Coherence Tomography Substudy were presented by…