Novel IL-6 Antibody Crushes CRP in High-risk ASCVD in Phase2
RESCUE, a phase II, trial presented by Paul M. Ridker, MD, Director of…
Colder Is Not Necessarily Better: CAPITAL CHILL Results
Key Points: Survivors of out of hospital cardiac arrest (OHCA) suffer very…
Role for Omecamtiv Mecarbil in Pts with EF
KEY POINTS: An experimental new therapeutic for heart failure, omecamtiv mecarbil is…
Revascularization Shows Benefit at 4 years in ISCHEMIA
Key Points: ISCHEMIA trial patients in the invasive management arm were assessed…
Acute alcohol consumption elevates risk of AF event
Presented as a Late Breaking Clinical Trial at the American College of…
Hyperinvasive Approach Improves Survival in Refractory Out-of-Hospital Cardiac Arrest
It goes without saying that refractory out of hospital cardiac arrest (OHCA)…
No Advantage to Catheter Ablation for Rhythm Control in Atrial Fibrillation
Atrial fibrillation and heart failure are two common, costly medical conditions that…
Hospital-level Intervention Did Not Improve Outcomes or Quality in HFrEF
Key Points: CONNECT-HF, one of the largest heart failure (HF) implementation science…
Pirfenidone Shown to Decrease Fibrosis in Patients with HFpEF
Key Points: Myocardial fibrosis has previously been associated with death and repeat…
Benefits of Sotagliflozin Across Full Spectrum of EF
KEY POINTS: Trials for those with heart failure with preserved ejection fraction…
Transfusion in AMI: More or Less?
A restrictive transfusion strategy may no longer be inferior to a liberal…
Sacubitril/Valsartan Not More Effective Than Valsartan alone in Advanced HF: LIFE trial
Key Points: This is the first study to assess the effects of…
0/1hr or 0/3hr hsTroponin T in Suspected ACS?
Key Points: Among patients with suspected acute coronary syndromes (ACS) and ischemia…
Low Dose Atorvastatin Did Not Reduce Composite Endpoint in Patients with COVID-19
INSPIRATION-S led by Behnood Bikdeli, MD, MS, and presented at the American…
ACTION-Coalition Trial: Therapeutic Dose of Anticoagulation Is Associated With Increased Risk of Bleeding and No Improvement in Clinical Outcomes Among Hospitalized COVID-19 Patients With Elevated D-Dimer Levels
ACTION presented at the American College of Cardiology 2021 meeting by Renato…
Paclitaxel-Coated Devices Not Associated with Higher Mortality, Results from SAFE-PAD Show
Paclitaxel-coated balloons had come under fire in recent years, after a meta-analysis…
No benefit to FFR-guided PCI over angiographic-guided PCI of Nonculprit Lesions after STEMI: Results from FLOWER-MI Show
Key Points: While FFR-guided PCI is superior in chronic coronary syndrome, its…
Aspirin Vs. Clopidogrel During Chronic Maintenance Monotherapy After Percutaneous Coronary Intervention: The Host Exam Randomized Controlled Trial
KEY POINTS: Clopidogrel is superior to aspirin as chronic maintenance therapy after…
Additional background and insight
Presented by Dr. Schuyler Jones, assistant professor of medicine, Duke University, and…