Clopidogrel Monotherapy Significantly Reduced MACE vs Aspirin Monotherapy Post-PCI: SMART-CHOICE 3
Key Points: Standard cardiology practice recommends aspirin monotherapy indefinitely after DAPT for…
FFR-Guided PCI Associated with Higher Rates of MI Compared to CABG in MVD: Five-Year Results from FAME-3
Key Points: The FAME 3 trial tested whether percutaneous coronary intervention (PCI)…
Sudden Cardiac Arrest Survival Worse in Minorities Among Young Athletes: RACER Cohort from 2010–2023
Key Points: This study presents updated national data from the Race Associated…
Altshock2: No Benefit to IABP in HF-Cardiogenic Shock
Key Points: Prior trials have demonstrated limited benefit to intra-aortic balloon pump…
No Benefit to Fluid Restriction in Chronic HF: FRESH UP
Key Points: While fluid restriction is a standard recommendation for patients with…
Biomarkers Show Limited Utility in Guiding Early TAVR Timing for Asymptomatic Severe AS: EARLY TAVR Trial
Key Takeaways: Elevated baseline NT-proBNP and hs-cTnT levels were associated with higher…
Autologous Bone Marrow Cell Therapy Failed to Meet Primary Endpoint in Ischemic Heart Failure: CardiAMP-HF
Key Takeaways: Intramyocardial autologous bone marrow cell therapy was safe in patients…
SHR-1918 Safe, Significantly Lowered LDL-C and Triglycerides in Poorly Controlled Hyperlipidemia
Key Takeaways: SHR-1918, an ANGPTL3 inhibitor, significantly reduced LDL cholesterol by approximately…
AI-Based ECG Model Enhances Detection of Heart Attack and Need for Coronary Revascularization
Key Takeaways: A deep learning ECG model significantly outperforms clinician interpretation in…
AI Accurately Detected Severe AS on TTE but Uptake Low Amongst Clinicians: Insights from a Randomized Crossover Study
Key Points: In a randomized crossover study, authors assessed whether artificial intelligence…
PRAGUE-25: Lifestyle Modification Plus Antiarrhythmic Drugs Inferior to Catheter Ablation In Obese Patients
Key Points: Obesity increases the risk of atrial fibrillation (AF) by 19–29%…
ZENITH Trial: Sotatercept Significantly Reduces Major Morbidity and Mortality Events in High-Risk PAH Patients
Key Points: Pulmonary arterial hypertension (PAH) is a progressive disease with poor…
SUMMIT: Tirzepatide Improved Renal Function in Patients with HFpEF, Obesity, and CKD
Key Points The SUMMIT randomized control trial demonstrated that tirzepatide significantly reduced…
EKSTROM Trial: Low-dose Colchicine Reduced Total Plaque Volume on CCTA, but Not Low Attenuation Plaque
Key Points The COLCOT trial demonstrated colchicine improved coronary plaque characteristics in…
Dapagliflozin Reduced LVMI in Patients with CKD : DECODE-CKD
Key Points The DECODE-CKD trial investigated the effects of SGLT-2 inhibitor Dapagliflozin…
Benefit from Intensive BP Control Across Frailty Statuses – A Post-Hoc Analysis of ESPRIT trial
Key Points The ESPRIT trial assessed whether the efficacy and safety of…
EARLY TAVR: Delayed TAVR Linked with Increased Risk of Death, Stroke, HF, or HFH Within 2 Years
Key Points: In this sub analysis of the EARLY TAVR trial, the…
Early, Short-Term Use of Rivaroxaban Plus DAPT Significantly Reduces Intracoronary Thrombus
Key Points: In the ARISE-ARMYDA 7 trial, 40 patients who presented with…
Solbinsiran, a Small Interfering RNA Targeting ANGPTL3,Reduced ApoB in Patients with Mixed Dyslipidaemia : PROLONG-ANG3
Key Points: Many patients with ASCVD are on LDL-lowering therapy, but many…
Health360x.ai Successfully Implemented Decentralized Clinical Trials in Underserved Populations
Key Points: Health360x.ai is an AI-powered digital health platform designed to scale…