Evolocumab Reduces CV Risk in Diabetic Patients Without ASCVD: VESALIUS-CV Trial
Key Points Lowering low-density lipoprotein cholesterol (LDL-C) is a cornerstone of cardiovascular prevention, with statins forming the foundation of therapy. While... Read more.
KARDINAL Trial: Tonlamarsen Reduces Angiotensinogen Levels but Does Not demonstrate additive SBP Benefit in in Single Versus Five Doses
Key Points Hypertension (HTN) remains a leading modifiable cardiovascular risk factor, with many patients exhibiting persistent elevations... Read more.
Home-Delivered DASH Diet Groceries Improve BP and LDL-C in African American Patients with Hypertension: The GoFreshRx Trial
Key Points Hypertension (HTN) disproportionately affects African- American adults in the United States, with structural barriers such as limited access to healthy... Read more.
Family-Based Intervention Reduced Blood Pressure in Adults in Rural China: The Healthy Family Program
Key Points: A community- and family-based intervention can reduce systolic blood pressure (SBP) across both hypertensive and normotensive adults in rural Chinese... Read more.
DASH Diet Patterned Groceries Help Reduce Blood Pressure in Black Adults: The GOFRESH Trial
Key Points: The GOFRESH trial, a parallel-group randomized study, was conducted to determine the effects of low sodium-DASH groceries on systolic BP. Home-delivered... Read more.
PCSK9-inhibitors Do Not Reduce Early Cardiac Allograft Vasculopathy: The CAVIAR Trial
Key Points The CAVIAR trial enrolled recent heart transplant recipients to receive either receive alirocumab 150 mg subcutaneously every 2 weeks or placebo, in addition... Read more.
A Liberal Transfusion Strategy Does Not Significantly Reduce MACE vs a Restrictive Strategy in High Cardiac Risk Patients: The TOP Trial
Key Points: In patients at high cardiac risk undergoing major vascular or general surgery and developing postoperative anemia, a liberal transfusion strategy (Hb... Read more.
Providing Healthy Food + Nutrition Counseling Improved Quality of Life in HF Patients: FOOD-HF Trial
Key Points: The FOOD‑HF Trial was a single center randomized trial that enrolled 150 patients within two weeks of discharge for acute HF. Participants were randomized... Read more.
Sacubitril/Valsartan Outperforms Enalapril in HFrEF due to Chronic Chagas Cardiomyopathy (CCC): The PARACHUTE-HF Trial
Key Points: Chronic Chagas cardiomyopathy (CCC) patients are underrepresented in heart failure (HF) trials and have a worse prognosis than other etiologies The PARACHUTE-HF... Read more.
An AI-enabled Stethoscope for Early Detection of Cardiac Conditions Increases Detection: TRICORDER
Key Points: Eighty percent of HF cases are diagnosed only during emergency hospital admissions, which negatively impacts survival rates and increases treatment costs... Read more.