Providing Healthy Food + Nutrition Counseling Improved Quality of Life in HF Patients: FOOD-HF Trial
Key Points: The FOOD‑HF Trial was a single center randomized trial that…
Tirzepatide Lowers MACE vs Dulaglutide in SURPASS-CVOT Patients With Heart Failure
Key Points In SURPASS-CVOT, tirzepatide was previously shown to be non-inferior to…
POLY-HF: Polypill for HFrEF Shows Promise in Reducing Medication Burden Among Underserved Patients
Key Points: Patients with heart failure with reduced ejection fraction (HFrEF) often…
A Liberal Transfusion Strategy Does Not Significantly Reduce MACE vs a Restrictive Strategy in High Cardiac Risk Patients: The TOP Trial
Key Points: In patients at high cardiac risk undergoing major vascular or…
STEP-HFpEF DM TRIAL: Semaglutide improves HF-related symptoms and results in greater weight loss among patients with obesity-related HFpEF and type 2 DM
Key Points: Semaglutide, a glucagon-like peptide-1 (GLP-1) analogue, has previously been shown…
ARIES-HM3: Aspirin avoidance Is safe and reduces bleeding events in patients with HM3 LVAD on VKA
Key Points: Since the advent of novel HeartMate 3 LVAD technology with…
TEAMMATE Trial: Everolimus with Low-Dose Tacrolimus to Prevent Rejection in Children after Cardiac Transplantation
Key Points This was the first randomized trial to evaluate the safety…
PRO-HF Sub-Study: Routine KCCQ-12 assessments in HF improves accuracy of provider assessment of patient health status.
Key Points Clinicians estimate heart failure (HF) health status using New York…
ECMO-CS: Early ECMO Does not Improve Outcomes in Severe Cardiogenic Shock
Key Points: ECMO has been used as a salvage strategy in severe…
IRONMAN: Intravenous Ferric Derisomaltose did not not meet primary endpoint in HFrEF
Key Points: Iron deficiency is common and a poor prognostic feature in…
COACH – A Patient-Risk Based Health System Intervention for Acute Heart Failure Care: The Comparison of Outcomes and Access to Care for Heart Failure (COACH) Trial
Key Points: HF patients frequently present to the ED for acute exacerbations,…
First-in-Human in vivo Crispr/Cas9 Editing of the TTR Gene by NTLA-2001 in patients with Transthyretin Amyloid Cardiomyopathy
Key Points: Transthyretin Amyloidosis (ATTR) is a highly morbid and often fatal…
Does Loop Diuretic Type Affect Clinical Outcomes in Heart Failure? Furosemide vs. Torsemide Compared in the TRANSFORM-HF Trial
Key points: Loop diuretics are routinely used to manage congestion in heart…
Sacubitril/Valsartan “wins” against ramipril in post-hoc analysis of PARADISE-MI
Key Points The PARADISE-MI trial randomized patients to receive sacubitril/valsartan or ramipril…
SODIUM-HF: Study Of Dietary Intervention Under 100 Mmol In Heart Failure
Key points: Sodium-HF sought to determine whether dietary sodium reduction reduces the…
Canaglifozin associated with Improved Quality of Life, Regardless of Ejection Fraction or Diabetes
CHIEF-HF Key Points: In the CHIEF-HF study, patients with HF of any…
CardioMEMS helps decrease Heart Failure events in specific populations: GUIDE-HF substudy shows
Key Points: In this follow-up study to GUIDE-HF, HF patients with hemodynamic-guided…
Empagliflozin does it again: Results from EMPEROR-PRESERVED
Key Points: Patients with chronic heart failure with preserved ejection fraction (HFpEF,…
COAPT Trial: Transcatheter Mitral Valve Repair Leads to Early and Sustained Health Improvements in Patients with Secondary Mitral Regurgitation
A study led by Dr. Suzanne Arnold published in the Journal of…