Two-Lead CRT-DX System Without Atrial Pacing Non-Inferior to Conventional Three-Lead CRT-D: Results from the CRT-NEXT Trial
Key Points: Cardiac resynchronization therapy (CRT) has become a cornerstone treatment for those with reduced ejection fraction and left bundle branch block. Standard... Read more.
AI-Based ECG Screening for Structural Heart Disease Demonstrates Moderate Performance in a Community Setting: Results from the PREVUE-VALVE Study
Key Points: With an aging population, the incidence and prevalence of valvular heart disease (VHD) and broader structural heart disease (SHD) are rising. Despite... Read more.
First-in-Human Gene Therapy for PKP2-Arrhythmogenic Cardiomyopathy Safe and Dose-Dependent PKP2 Protein Restoration: HEROIC-PKP2 Trial
Key Points: Arrhythmogenic cardiomyopathy (ACM) is a rare inherited cardiac disorder characterized by progressive fibro-fatty replacement of the myocardium, ventricular... Read more.
Lung Impedance–Guided Therapy Reduces Hospitalizations and Mortality in HFpEF: Results from the IMPEDANCE-HFpEF Trial
Key Points: Patients with heart failure with preserved ejection fraction (HFpEF) are often marred by significant morbidity with recurrent hospitalizations. A critical... Read more.
Transcutaneous Autonomic Neuromodulation Is Safe But Did Not Reduce BP in Uncontrolled Hypertension: SCRATCH-HTN
Key Points: Despite the availability of multiple effective antihypertensive drug classes, blood pressure (BP) control remains a persistent public health challenge,... Read more.
FFR-Guided PCI Associated with Higher Rates of MI Compared to CABG in MVD: Five-Year Results from FAME-3
Key Points: The FAME 3 trial tested whether percutaneous coronary intervention (PCI) could offer comparable long-term outcomes to coronary artery bypass grafting... Read more.
Sudden Cardiac Arrest Survival Worse in Minorities Among Young Athletes: RACER Cohort from 2010–2023
Key Points: This study presents updated national data from the Race Associated Cardiac Event Registry (RACER) on cardiac arrest incidence and outcomes during long-distance... Read more.
AI Accurately Detected Severe AS on TTE but Uptake Low Amongst Clinicians: Insights from a Randomized Crossover Study
Key Points: In a randomized crossover study, authors assessed whether artificial intelligence (AI) can improve accuracy of cardiologists when evaluating echocardiograms... Read more.
Routine Cerebral Embolic Protection Did Not Reduce Incidence of Peri-procedural Stroke in TAVI: BHF PROTECT-TAVI
Key Points: Stroke remains one of the most feared complications of transcatheter aortic valve implantation (TAVI), prompting interest in cerebral embolic protection... Read more.
TAVR with Trilogy System Safe and Effective for Aortic Regurgitation: Updated Results from ALIGN-AR
Key Points: Transcatheter aortic valve replacement for aortic valve disease has largely focused on those with aortic stenosis. In pure, native-valve aortic regurgitation,... Read more.