CLASP-TR demonstrates significant improvement in tricuspid regurgitation up to one year after procedure.
Key Points Tricuspid regurgitation is a debilitating valve disorder characterized by shortness…
Uncoupling Hemostasis from Thrombosis: A Promising Comparison of Oral FXIa Inhibitor Asundexian Versus Apixaban in Patients with Atrial Fibrillation – But More Data Are Needed.
Key Points Selective XIa inhibitor Asundexian may innovate the field of oral…
Alirocumab initiation after MI associated with lower plasma atheroma volume: PACMAN-AMI
Key Points PCSK-9 inhibitors have emerged as a viable treatment option patients…
Mavacamten improves LVOT gradients in patients with HCM: EXPLORER-LTE
Key Points: In the EXPLORER-LTE study, patients with severely symptomatic obstructive HCM…
Vupanorsen shown to effectively decrease non-HDL cholesterol in patients already on statins: TRANSLATE-TIMI 70
Key Points: A need for various lipid-lowering agents to combat high cholesterol…
Reduction in Lp(a) possible with siRNA therapy: APOLLO
Key Points: In the Phase I APOLLO study, patients without known ASCVD…
SODIUM-HF: Study Of Dietary Intervention Under 100 Mmol In Heart Failure
Key points: Sodium-HF sought to determine whether dietary sodium reduction reduces the…
An Old Drug with New Tricks: Tranexamic Acid Decreases Bleeding Events in Surgery, POISE-3 Suggests
Key Points: Tranexamic acid, given to patients undergoing noncardiac surgery, was associated…
VALOR-HCM: Treatment with mavacamten decreased need for septal reduction therapy in patients with hypertrophic cardiomyopathy.
Key Points: In the VALOR-HCM study, patients with severely symptomatic obstructive HCM…
EMPULSE: Empagliflozin improves outcomes in all Heart Failure admissions
Key Points: In the EMPULSE study, patients admitted with acute HF of…
Icosapent Ethyl Shows Signal but Not Significance for Clinical Improvement in COVID-19 Outpatients – The PREPARE-IT 2 Trial
Key Points: Icosapent ethyl (IPE) had previously shown a signal for improvement…
Ticagrelor Finds a Quick, Effective Reversal Agent in Bentracimab: REVERSE-IT Early Data
Key Points: To date, P2Y-12 inhibitors do not have a commercially approved…
AXIOMATIC-TKR: Milvexian a Success for Prevention of Venous Thromboembolism after Elective Knee Arthroplasty
Key Points: Milvexian is a first-in-class rapidly absorbed oral Factor XIa inhibitor…
Aspirin Not Proven to Prevent Dementia and Cognitive Impairment – Results of the ASCEND Trial
Key Points: The ASCEND trial sought to determine whether low-dose aspirin could…
Can Your Fitbit Accurately Detect Atrial Fibrillation? Results of The Fitbit Heart Study
Key Points Wearable technologies have optical photoplethysmography (PPG) sensors to measure heart…
Canaglifozin associated with Improved Quality of Life, Regardless of Ejection Fraction or Diabetes
CHIEF-HF Key Points: In the CHIEF-HF study, patients with HF of any…
Avoiding triggers for Atrial Fibrillation has no effect on Quality of Life: results from I-STOP-A-FIB show
Key Points: Interest in this study was generated by patients with atrial…
EHR-Derived Risk Estimates for Clinicians Do Not Change Heart Failure Patient Outcomes – The REVeAL-HF Trial
Key Points: Previously, the impact of risk prediction on clinical decision-making and…
Coffee-drinkers rejoice: caffeine consumption not associated with atrial arrhythmias (in young, healthy patients): CRAVE shows
Key Points: Conventional medical wisdom warns against excessive coffee and/or caffeine consumption…
Multifaceted Interventions Delivered by Rural Physicians Significantly Reduce Hypertension Rates in Rural China: CRHCP
Key Points Rural areas represent particularly vulnerable areas for the control of…