AMULET superior to WATCHMAN in peridevice leak at 12 months: clinical impact unknown
Key Points The AMULET Left Atrial Appendage Occluder was shown to be…
SURTAVI: self-expanding TAVR continues to perform against SAVR 5 years out
Key Points The SURTAVI trial randomized patients at intermediate risk for aortic…
STOP-DAPT 2 Total Cohort Study: needle moving closer to one month DAPT strategy
Despite advances in therapy, the choice and duration of antiplatelet therapy following…
Left atrial appendage closure is noninferior to NOACs for atrial fibrillation: PRAGUE-17
Key Points: In the PRAGUE-17 study, patients with non-valvular atrial fibrillation were…
Plug-based vascular closure device associated with more complications: CHOICE-CLOSURE
In patients with severe aortic stenosis (AS) undergoing transfemoral transcatheter aortic valve…
Abbreviated DAPT can be safe for patients with high bleeding and ischemic risk: MASTER-DAPT substudy
Key Points: In this pre-specified MASTER DAPT sub-study, patients with high bleeding…
Sweet news for new stent: SUGAR trial finds polymer-free stent non-inferior to ZES in patients with diabetes.
Key Points: Patients with diabetes who undergo PCI are more likely to…
PCI guided by Quantitative Flow Reserve Superior to Standard Angiography: FAVOR III China
Key Points: Quantitative Flow Reserve (QFR) is a non-pressure wire method of…
FAME 3: PCI does not meet noninferiority to CABG in patients with three-vessel disease.
Key Points: All-comers with three vessel disease were randomized to undergo FFR-guided…
STOP-DAPT 2 ACS: 1 month DAPT followed by clopidogrel monotherapy does not quite cut it when it comes to ACS
Key Points: The original STOP-DAPT trial randomized patients to receive either 12…
Influenza Vaccination after Myocardial Infarction Should Become Standard of Care – Results of the IAMI Trial
Key Points: Prior observational and small randomized studies suggested that influenza vaccine…
When Treating Blood Pressure in Older People – How Low Should We Go? Results from the STEP Study: Intensive vs. Standard Blood Pressure Control Among Older Hypertensive Patients
Key Points: The STEP Study was a multicenter, randomized, controlled trial which…
Amulet IDE: a new left atrial appendage occlusion device enters the market for patients with atrial fibrillation and contraindications to anticoagulation.
Key points: • The Amulet IDE is an open-label clinical trial that…
ILR use led to increased diagnosis of Atrial Fibrillation, but no reduction in stroke or arterial embolism noted: Results from LOOP
Key Points: • In the LOOP trial, patients at high risk of…
Salt substitutes decrease rates of stroke, cardiovascular events, and mortality: results from SSaSS
Key Points: The Salt Substitute and Stroke (SSaSS) study compared the effect…
ACST-2: Largest trial to date comparing carotid artery stenting to carotid endarterectomy finds no difference in disabling stroke at 5 years.
Key Points: Carotid artery stenting and carotid endarterectomy have both been employed…
One month of dual antiplatelet therapy after PCI non-inferior to standard duration: results from MASTER DAPT.
Key Points: Patients with high bleeding risk who were treated with PCI…
TOMAHAWK: no benefit in immediate angiography after out of hospital cardiac arrest without ST segment elevation
Key Points: In patients with resuscitated out-of-hospital cardiac arrest (OHCA) of potential…
Systematic FFR in patients undergoing coronary angiography did not improve outcomes at 1 year: Results from RIPCORD-2.
Key Points: Patients undergoing coronary angiography were randomized to undergo fractional flow…
APAF-CRT: AV junction ablation followed by biventricular pacing provides a significant mortality benefit among some patients with symptomatic atrial fibrillation
Key points: • The APAF-CRT trial was a two-phase trial conducted among…