META-AF Trial – Metformin Reduces Arrhythmia Recurrence After AF Ablation in Overweight, Non-diabetic Patients
Key Points: Obesity is a well-established risk factor for atrial fibrillation (AF)…
FLAME: FlowTriever use for PE associated with decreased in-hospital adverse outcomes
Key Points: Mortality in high-risk PE remains unacceptably high (25%) despite advances…
CLEAR Outcomes – Bempedoic Acid reduces Cardiovascular Events among Statin-Intolerant Patients
Key Points Bempedoic acid, an ATP citrate lyase inhibitor, has been shown…
It’s Time to Randomize: Smartphone-Based Screening for Atrial Fibrillation – The Siteless, Digital, Randomized eBRAVE-AF Trial
Key Points Wearable technologies based on photoplethysmographic measurements of irregular pulses can…
Artificial Intelligence can improve detection of severe aortic stenosis from echocardiograms: AI-ENHANCED AS shows.
Key Points Aortic stenosis, despite being life-threatening, is often underdiagnosed. It is…
Acetazolamide results in improved decongestion, faster: results from ADVOR
Key Points: Residual decongestion after a hospitalization for acute decompensated heart failure…
More Evidence For the Newest Guideline Directed Medical Therapy Pillar – Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (The DELIVER Trial)
Key Points: The use of sodium-glucose cotransporter-2 inhibitor (SGLT2i) in heart failure…
Routine PCI confers no added benefit in severe left ventricular dysfunction: REVIVED
Key Points REVIVED is the first large scale clinical trial to assess…
VALOR-HCM: Treatment with mavacamten decreased need for septal reduction therapy in patients with hypertrophic cardiomyopathy.
Key Points: In the VALOR-HCM study, patients with severely symptomatic obstructive HCM…
Left atrial appendage closure is noninferior to NOACs for atrial fibrillation: PRAGUE-17
Key Points: In the PRAGUE-17 study, patients with non-valvular atrial fibrillation were…
ACST-2: Largest trial to date comparing carotid artery stenting to carotid endarterectomy finds no difference in disabling stroke at 5 years.
Key Points: Carotid artery stenting and carotid endarterectomy have both been employed…
One month of dual antiplatelet therapy after PCI non-inferior to standard duration: results from MASTER DAPT.
Key Points: Patients with high bleeding risk who were treated with PCI…
TOMAHAWK: no benefit in immediate angiography after out of hospital cardiac arrest without ST segment elevation
Key Points: In patients with resuscitated out-of-hospital cardiac arrest (OHCA) of potential…
APAF-CRT: AV junction ablation followed by biventricular pacing provides a significant mortality benefit among some patients with symptomatic atrial fibrillation
Key points: • The APAF-CRT trial was a two-phase trial conducted among…
MRI-guided ablation no better than conventional PVI for Atrial Fibrillation
Key Points: DECAAF-1 showed that higher volumes of atrial tissue fibrosis on…
Haemodynamic Guided Heart Failure Management as a Hospitalization Reduction Strategy – the GUIDE-HF Tria
KEY POINTS: · CardioMEMS, a wireless, battery-free pressure sensor implanted in the…
STOP AF First Trial: Cryoballoon Ablation Is Superior to Antiarrhythmic Drug Therapy for the Prevention of Atrial Arrhythmia Recurrence in Patients With Paroxysmal Atrial Fibrillation
A recent trial by Dr. Oussama M. Wazni, published in the New…
TIPS-3 Trial: The Combination of Polypill and Aspirin Administered to Patients at Intermediate Risk Led to a Lower Incidence of Cardiovascular Events Compared With Double Placebo
A recent trial by Dr. Salim Yusuf, published in The New England Journal…
EMPEROR-Reduced Trial: Empagliflozin Use Was Associated With a Better Clinical Outcomes Among Patients With Heart Failure and a Reduced Ejection Fraction
A recent study by Dr. Milton Packer, published in Circulation, demonstrated that…
COACT Trial Shows Immediate Coronary Angiography Does Not Change the 1-Year Clinical Outcomes of Patients After Cardiac Arrest Without ST-Segment Elevation
A trial by Dr. Jorrit S. Lemkes, published in JAMA Cardiology, demonstrated…