The ADVENT of Pulsed Field Ablation for Atrial Fibrillation: just as effective and safe as traditional thermal ablation, but faster
Key Points: ADVENT was the first randomized controlled trial comparing pulsed field…
STOPDAPT-3: Prasugrel monotherapy after PCI with DES not superior to DAPT for major bleeding but non-inferior for CV events
Key Points: This trial randomized 6,000 patients with high bleeding risk or…
FIRE: Complete revascularization better than culprit-only strategy for elderly with MI and MVD
Key Points The FIRE trial aimed to address the lack of evidence…
Meta-analysis demonstrates that IV Iron is associated with reduced HF hospitalizations in HF patients with iron deficiency
Key Points: Iron-deficiency is common in heart failure (HF) and associated with…
ECLS-SHOCK: ECMO does not reduce mortality in acute MI-related cardiogenic shock compared to control
Key Points: The use of ECLS has increased substantially over the past…
QUEST: Chinese Herbal Medicine (Qiliqiangxin) reduces heart failure hospitalizations and cardiovascular mortality in HFrEF
Key Points: Qiliqiangxin is a traditional Chinese herbal medicine extract which has…
HEART-FID Trial: Ferric Carboxymaltose resulted in modest improvement in hierarchical outcomes but did not reach statistical significance
Key Points: Prior data suggest that heart failure with reduced ejection fraction…
Wait no more – HFrEF patients with high RV pacing burden from pacemakers or defibrillators should be promptly upgraded to CRT devices: insights from the BUDAPEST-CRT Upgrade Study
Key Points: A high burden of right ventricular pacing among patients with…
STEP-HFpEF: Semaglutide reduces heart failure symptoms and body weight in HFpEF patients at one year
Key Points: More than 80% of patients with HFpEF are overweight or…
COP-AF: Colchicine did not reduce AF or myocardial injury after non-cardiac surgery, but post-hoc analysis suggest benefit in composite outcomes
Key Points This trial randomizing patients aged 55 or older to colchicine…
NOAH-AFNET 6: No benefit of oral anticoagulation among patients with atrial high-rate episodes in the absence of confirmed AF
Key Points This trial randomized elderly patients without a known diagnosis of…
HOST-IDEA: 3-Month DAPT Noninferior to 12-Month DAPT in Patients Undergoing PCI using third-generation stents
Key Points: Among patients undergoing PCI using third-generation DES with ultrathin struts…
UK Biobank Analysis: Self-reported LCHF Diet May be Linked to Cardiac Events
Key Points: In spite of the increase popularity of low-carbohydrate high-fat diet…
hsCRP is a Stronger Predictor of CV Events and Death than LDL-C in High-Risk Patients on Statins
Key Points: Both inflammatory risk and hyperlipidemia and crucial risk factors for…
FREEDOM COVID: Therapeutic dose anticoagulation does not reduce MACE in non-critically ill COVID-19 patients
Key Points: There have been conflicting data on the role and recommended…
STELLAR: Sotatercept improves 6MWD in PAH patients and WHO FC II-III
Key Points: Sotatercept is a novel activin signaling inhibitor which was designed…
Dapagliflozin Reduces PCWP at Rest and Exercise, Plasma Volume, and Weight in HFpEF patients
Key Points: SGLT2i therapy reduces HF hospitalizations and CV mortality in HFpEF,…
BMAD Trial: Use of data from μCor, A Novel Wearable Sensor, reduces HF readmissions following a recent HF hospitalization
Key Points: The μCor monitor is a novel device that uses…
A Novel, Oral, PSCK-9 Inhibitor Showed Significant and Dose-dependent Reduction of LDL compared to Placebo
Key Points -Lowering LDL-C is known to reduce the risk of ASCVD…
LIVE HCM Trial: Vigorous Exercise in Patients with HCM Not Associated with Increased Risk of Adverse Cardiac Events
Key Points -HCM is the most common cause of sudden cardiac death…