TAVI Superior to Surgical Aortic Valve Replacement in Women: RHEIA Trial
Key Points: The RHEIA trial found that TAVI was superior to surgical…
SWEDEGRAFT Trial: No Advantage of No-Touch vs Conventional Vein Harvesting in Coronary Artery Bypass Surgery
Key Points: The SWEDEGRAFT study is a prospective, binational multicenter, open-label, registry-based…
Transcatheter Mitral-valve Repair Lowers Hospitalization or CV Death vs Medical Therapy Alone in HF with Moderate to Severe MR: RESHAPE-HF2 Trial
Key Points: The Mitral Transcatheter Edge-to-Edge Repair (M-TEER) procedure with the MitraClip…
Continuation of Anticoagulation Non-Inferior to Interruption during TAVI: POPular PAUSE TAVI Trial.
Key Points: Many patients who undergo transcatheter aortic-valve implantation (TAVI) have an…
Pooled Analysis Showed Semaglutide Reduced Combined CV death or Worsening HF and Worsening HF alone but No Significant Effect on CV Death
Key Points: Heart failure with mildly reduced or preserved ejection fraction (hereafter…
Transcatheter Edge-To-Edge Repair Is Non-Inferior To Surgery In Patients With Secondary Mitral Regurgitation: MATTERHORN Trial
Key Points: The MATTERHORN trial found that the transcatheter edge-to-edge repair (TEER)…
T-TEER Significantly Reduced the Severity of Secondary Tricuspid Regurgitation and Improved Quality of Life. TRI-FR Trial
Key Points: The TRI.FR trial found that tricuspid transcatheter edge-to-edge repair (T-TEER)…
ABYSS – Beta Blocker Interruption in Post-Myocardial Infarction Patients
Key Points: In the ABYSS trial, 3700 patients who had a left…
Vitrusiran Reduces Risk of Death and CV Events in Patients with ATTR-CM
Key Points: ATTR amyloid cardiomyopathy, resulting from accumulation of TTR amyloid protein…
Consistent Renal Benefits of Semaglutide in CKD and T2DM Patients With or Without SGLT2 Inhibitors Use. FLOW Trial
The FLOW trial showed that among patients with chronic kidney disease (CKD)…
Tirzepatide Reduced Apnea-hypopnea Index and Weight in Obese Patients with Moderate Sleep Apnea: SURMOUNT-OSA Trials
Obstructive sleep apnea is associated with cardiovascular complications and is seen more…
LENS Trial: Fenofibrate Significantly Reduced Progression of Diabetic Retinopathy vs Placebo.
- Findings from cardiovascular trials suggested that fenofibrate therapy may reduce the…
IVUS-Guided DES Reduced MACE at 1 year Compared to Angiography-Guided PCI: IVUS-ACS Trial
Key Points: The IVUS-ACS trial assessed whether the use of intravascular ultrasound…
IVUS -DBC: IVUS-guided drug-coated balloon angioplasty improves primary patency
Key Points: One-year success rates of angioplasty in peripheral artery disease (PAD)…
A technology assisted Web App allowed >90% of consumers to correctly self-select for statin use and achieve clinically important LDL-C reduction
Key Points: Nonprescription statin access may help statin-eligible patients receive appropriate treatment.…
PROACT: Enalapril Does Not Mitigate Anthracycline Toxicity in Breast Cancer and NHL
Key Points: Anthracycline toxicity is an important cause of cardiomyopathy; it is…
Topical TXA Does Not Reduce Peri-Operative Seizures but Increases Risk of Transfusion in Cardiac Surgery Compared to Intravenous TXA
Key Points: IV TXA is used to prevent peri-operative bleeding in cardiac…
IMPROVE-HCM: Cardiac Mitotrope -Ninerafaxstat- Improves Functional Capacity in Symptomatic Non-Obstructive HCM
Key Points: Despite the high symptomatic burden, very few effective treatments exits…
A Restrictive Benzodiazepine Strategy During Cardiac Surgery Does Not Reduce Post-Operative Delirium
Key Points: Benzodiazepine use contributes to delirium before and after cardiac surgery,…
TRAVERSE: Transseptal approach to LV ablation results in fewer cerebral emboli compared to retrograde aortic approach
Key Points: Among patients who undergo endocardial ablation for left ventricular arrythmias,…