Metanalysis: OCT or IVUS is associated with improved outcomes compared to angiography alone
Key Points This metanalysis integrating data from ILUMIEN IV and OCTOBER Trials with 18 prior randomized trials found that intravascular imaging (IVI) with intravascular... Read more.
Addressing the Triple Threat: Proactive Screening Resulted in Improved Early Detection of Coronary Artery Disease, Atrial Fibrillation, and Heart Failure in the RED-CVD Trial
Key Points: Tertiary screening for chronic cardiovascular disease as a means to reduce morbidity, mortality, and economic burden on the healthcare system has been... Read more.
OCTOBER Trial: OCT Reduces MACE in complex bifurcation lesions
Key Points This trial randomizing patients with stable angina, unstable angina (UA), or non–ST-segment elevation myocardial infarction (NSTEMI) and a true bifurcation... Read more.
ONCO-DVT– 1 Year of Anticoagulation With Edoxaban Is Superior To 3-Months In Cancer Patients With Distal DVT
Key Points: The optimal duration of therapy for distal deep vein thrombosis (DVT) among patients with an active malignancy is unknown. ONCO-DVT was the first randomized... Read more.
ILUMIEN IV: OCT-guided complex PCI led to increased minimal stent area, improved safety, and lower in-stent thrombosis rates but no difference in target vessel failure at 2 years
Key Points This trial randomizing patients with diabetes and/or complex lesions to optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI)... Read more.
MULTISTARS AMI Trial: Immediate Complete Multivessel PCI non-inferior to staged approach in patients with STEMI and MVD
Key Points: It is well known that patients with STEMI often have multivessel disease (MVD) and those with MVD have worse outcomes compared to patients without it.... Read more.
FRAIL-AF: Switching to NOACs in Frail Elderly with AF Linked to Increased Bleeding
Key Points: The FRAIL-AF trial is an open-label, randomized controlled trial that randomized frail adults (75 years or older) who were on VKA for atrial fibrillation... Read more.
ARREST: Transfer to a cardiac arrest center instead of the nearest ED does not improve mortality in OHCA patients
Key Points: Sudden cardiac death causes a fifth of all deaths in industrialized countries, but survival to hospital discharge remains low. Transfer to a specialized,... Read more.
ATTRibute-CM: Acoramidis Linked to Improved clinical outcomes in transthyretin amyloid cardiomyopathy
Key Points: Transthyretin amyloid cardiomyopathy develops because of mis-folded proteins infiltrating the myocardium, leading to clinical heart failure. Currently,... Read more.
The ADVENT of Pulsed Field Ablation for Atrial Fibrillation: just as effective and safe as traditional thermal ablation, but faster
Key Points: ADVENT was the first randomized controlled trial comparing pulsed field ablation (PFA) to conventional strategies for ablation (including either radiofrequency... Read more.