Tirzepatide Lowers MACE vs Dulaglutide in SURPASS-CVOT Patients With Heart Failure
Key Points In SURPASS-CVOT, tirzepatide was previously shown to be non-inferior to…
DAPT-MVD: Extended DAPT reduces MACCE in patients with multi-vessel disease after DES
Key Points: The optimal duration and choice of dual antiplatelet therapy (DAPT)…
NOAC Monotherapy Non-Inferior to Combination Therapy for Net Adverse Clinical events in AF Patients Post–DES: ADAPT AF-DES Trial
Key Points The ADAPT AF-DES randomized trial compared NOAC monotherapy (apixaban or…
Prasugrel Might be a Better Choice than Ticagrelor For DAPT after PCI for Patients with Diabetes and MVD: The TUXEDO-2 Trial
Key Points TUXEDO-2 directly compared ticagrelor vs prasugrel based DAPT in 1,800…
ABLATION Trial – Biatrial Ablation During Mitral Valve Surgery Better than LA Ablation Alone
Key Points: Persistent atrial fibrillation (AF) is common among patients with rheumatic…
Early Surgery Provides Durable Survival Advantage in Asymptomatic Severe Aortic Stenosis: Final 10-Year Outcomes from the RECOVERY Trial
Key Points: Over a decade of follow-up, early surgical aortic valve replacement…
OPTIMA-AF Trial – One-month Dual Therapy After PCI Non-inferior to 12 Months, With Lower Bleeding in AF Patients
Key Points: • In patients with atrial fibrillation (AF) undergoing PCI, prolonged…
DARE-AF Trial: Dapagliflozin Did Not Reduce AF Burden After Catheter Ablation
Key Points: SGLT2 inhibitors have shown potential antiarrhythmic benefits in cardiometabolic disease,…
VESALIUS-CV: PCSK9-Inhibitor Evolocumab Reduces MACE for Primary Prevention
Key Points: PCSK9-inhibitors – including evolocumab – are highly effective LDL-C–lowering medications…
Percutaneous Coronary Intervention Improved Symptoms in Stable Angina: ORBITA-2 trial
Key points: PCI is often performed for chronic stable angina, but current…
OCTIVUS: OCT- Guided PCI is non-inferior to IVUS-Guided PCI for Clinical Outcomes
Key Points This pragmatic trial randomizing patients to optical coherence tomography (OCT)-guided…
Metanalysis: OCT or IVUS is associated with improved outcomes compared to angiography alone
Key Points This metanalysis integrating data from ILUMIEN IV and OCTOBER Trials…
UNIVERSAL: Routine ultrasound guidance of femoral vascular access did not reduce bleeding or vascular complications but did facilitate access
Key Points: Femoral access is used for 30% of all coronary procedures,…
FAME 3 sub-study shows no difference in quality of life between FFR-guided PCI and CABG.
Key Points PCI has yet to be shown to be superior to…
More Improvement in Residual Angina and Quality of Life in Complete Revascularization.
Key Points The COMPLETE trial, published in 2019, demonstrated that in patients…
LRT Trial: Transcatheter Aortic Valve Replacement In Low Risk Patients with Symptomatic Severe Aortic Stenosis Appears To Be Safe At 1 Year
A study led by Dr. Ronald Waksman showed that in low-risk patients…
BIO-RESORT TRIAL: Lower Stent Strut Thickness Associated with Lower Rates of Repeat Revascularization
A prespecified analysis of the BIO-RESORT trial demonstrated that patients stent in…
REVELATION: Drug-Coated Balloon Is Non-Inferior to Drug-Eluting Stent in Terms of Functional Outcome by 9 Months In Patients with STEMI
A randomized controlled trial led by Dr. Nicola Vos published in JACC:…
New Study Involving 95,000 Stents Shows Outcomes of Bioabsorbable Polymer Drug-Eluting Stents Not Better than Permanent Drug-Eluting Stents in Reducing Stent Thrombosis and Restenosis
In a study published in the European Heart Journal, Dr. Sergio Buccheri…
COAPT Trial: Transcatheter Mitral Valve Repair Leads to Early and Sustained Health Improvements in Patients with Secondary Mitral Regurgitation
A study led by Dr. Suzanne Arnold published in the Journal of…