CorCMR: Stress Cardiac MRI Uncovers Hidden Angina and Improves Quality of Life in Patients Without Obstructive Coronary Disease
Key Points: Stress cardiac MRI (CMR) enhanced diagnostic accuracy for patients with…
CELEBRATE: Early Pre-hospital Subcutaneous Zalunfiban Improves Coronary Patency and Outcomes in STEMI Without Increasing Severe Bleeding
Key Points: Early pre-hospital administration of subcutaneous zalunfiban improved coronary patency and…
FAVOR IV-QVAS: Angio-FFR–Guided CABG During Valve Surgery Improves Outcomes
Key Points: The FAVOR IV-QVAS trial tested the hypothesis physiology-guided coronary artery…
Early Surgery Provides Durable Survival Advantage in Asymptomatic Severe Aortic Stenosis: Final 10-Year Outcomes from the RECOVERY Trial
Key Points: Over a decade of follow-up, early surgical aortic valve replacement…
CLOSURE-AF: Left Atrial Appendage Closure Fails to Achieve Noninferiority to Medical Therapy in AF Patients With High Bleeding Risk
Key Points: The CLOSURE AF study compared catheter-based left atrial appendage closure…
Biomarkers Show Limited Utility in Guiding Early TAVR Timing for Asymptomatic Severe AS: EARLY TAVR Trial
Key Takeaways: Elevated baseline NT-proBNP and hs-cTnT levels were associated with higher…
Autologous Bone Marrow Cell Therapy Failed to Meet Primary Endpoint in Ischemic Heart Failure: CardiAMP-HF
Key Takeaways: Intramyocardial autologous bone marrow cell therapy was safe in patients…
SHR-1918 Safe, Significantly Lowered LDL-C and Triglycerides in Poorly Controlled Hyperlipidemia
Key Takeaways: SHR-1918, an ANGPTL3 inhibitor, significantly reduced LDL cholesterol by approximately…
AI-Based ECG Model Enhances Detection of Heart Attack and Need for Coronary Revascularization
Key Takeaways: A deep learning ECG model significantly outperforms clinician interpretation in…
0/1-Hour Algorithm Safe and Effective for Rapid Chest Pain Assessment in the ED: DROP-Asian ACS Trial
Key Takeaways: The 0/1-hour hs-cTn algorithm is safe, non-inferior to usual care,…
Routine Orbital Atherectomy Does Not Improve Outcomes vs Balloon Angioplasty for Severely Calcified Coronary Lesions: ECLIPSE Trial
Key Takeaways: Orbital atherectomy as a routine lesion preparation strategy prior to…
AI-Quantitative CT Coronary Plaque Features Indicate Higher Relative CV Risk in Women: CONFIRM2 Registry
Key Takeaways: AI-based quantitative coronary plaque assessments significantly improve risk prediction for…
First-in-Human Gene Therapy (TN-201) Shows Promising Results in MYBPC3-Associated HCM
Key Takeaways: TN-201, a first-in-class gene therapy, was well tolerated and showed…
Artificial Intelligence Enables Novices to Perform Diagnostic-Quality Echocardiography: HeartFocus Study
Key Takeaways: AI-guided echocardiography enables novice users to obtain diagnostic-quality cardiac images…
Survival After Sudden Cardiac Arrest Improves in Young Athletes, but Racial Disparities Persist
Key Takeaways: Survival from sudden cardiac arrest among young competitive athletes increased…