Evolocumab Effect on Plaque Characteristics in Stable CAD Patients
Key Points The YELLOW III study aimed to assess the effect of…
No difference in Heart Failure Outcomes with Advanced Imaging modalities vs SPECT: The AIMI-HF Trial
Key Points: Imaging may be underused in patients with ischemic heart failure…
Viability Not Linked to Survival or LV improvement: The REVIVED-BCIS2 Randomized Trial
Key Points: -It is unclear whether myocardial viability tests should be used…
Atorvastatin Reduced Left Ventricular Dysfunction From Anthracyclines: The STOP-CA Trial
Key Points -Anthracycline therapy is associated with the development of heart…
RIVARAD: Post-Procedural Rivaroxaban Use After Radial Access for Coronary Procedures Reduces Radial Artery Occlusion at 30 Days
Key Points: Radial artery occlusion (RAO) is the most common complication after…
EPIC-STEMI: Early Routine PCSK-9 Use Added to High Intensity Statin Reduces LDL after Primary PCI for STEMI
Key Points: Early high-intensity statin therapy is standard of practice in acute…
Extended outcomes of BEST: No difference in MACE between PCI and CABG in MVD at 12 years, but higher repeat revascularization and spontaneous MI in PCI arm
Key Points: Previous studies have demonstrated the superiority of CABG over PCI…
FLASH: The FlowTriever system has an excellent safety profile in the treatment of pulmonary embolism
Key Points: Mortality for acute PE remains high. While percutaneous mechanical thrombectomy…
UNIVERSAL: Routine ultrasound guidance of femoral vascular access did not reduce bleeding or vascular complications but did facilitate access
Key Points: Femoral access is used for 30% of all coronary procedures,…
PADN-CFDA: Pulmonary artery denervation in addition to PDE-5i therapy improves exercise capacity in patients with pulmonary arterial hypertension
Key Points: Pulmonary artery denervation (PADN) has never been studied with a…
RADIANCE II: Endovascular ultrasound denervation met primary/secondary efficacy BP lowering endpoints at 2 months
Key Points: Endovascular ultrasound denervation (uRDN) is a potentially useful technique in…
Amulet IDE: Continued safety and effectiveness of the Amulet LAA occluder device at three years in patients with nonvalvular atrial fibrillation
Key Points: In 2021, the Amulet IDE study demonstrated that the novel…
CLASP IID: The PASCAL system is a safe and beneficial therapy for severe degenerative mitral regurgitation
Key Points: The MitraClip system has been established as a robust platform…
PROTECTED TAVR: No Overall Stroke Reduction With Embolic Protection Devices in TAVR, But Fewer Disabling Strokes
Key Points: Stroke is a feared complication of TAVR. However, the potential…
Stem Cells Did Not Decrease Heart Failure Readmissions in DREAM-HF
Key Points: In the DREAM-HF study, patients with persistent NYHA II-III HFrEF…
EMPULSE: Empagliflozin improves outcomes in all Heart Failure admissions
Key Points: In the EMPULSE study, patients admitted with acute HF of…
EMPEROR PRESERVED sub-study shows no difference in outcomes when stratified by ejection fraction.
Key Points: In the original EMPEROR-PRESERVED study, patients with chronic heart failure…
Icosapent Ethyl Shows Signal but Not Significance for Clinical Improvement in COVID-19 Outpatients – The PREPARE-IT 2 Trial
Key Points: Icosapent ethyl (IPE) had previously shown a signal for improvement…
Ticagrelor Finds a Quick, Effective Reversal Agent in Bentracimab: REVERSE-IT Early Data
Key Points: To date, P2Y-12 inhibitors do not have a commercially approved…
AXIOMATIC-TKR: Milvexian a Success for Prevention of Venous Thromboembolism after Elective Knee Arthroplasty
Key Points: Milvexian is a first-in-class rapidly absorbed oral Factor XIa inhibitor…