Extended outcomes of BEST: No difference in MACE between PCI and CABG in MVD at 12 years, but higher repeat revascularization and spontaneous MI in PCI arm
Key Points: Previous studies have demonstrated the superiority of CABG over PCI…
FLASH: The FlowTriever system has an excellent safety profile in the treatment of pulmonary embolism
Key Points: Mortality for acute PE remains high. While percutaneous mechanical thrombectomy…
PADN-CFDA: Pulmonary artery denervation in addition to PDE-5i therapy improves exercise capacity in patients with pulmonary arterial hypertension
Key Points: Pulmonary artery denervation (PADN) has never been studied with a…
RADIANCE II: Endovascular ultrasound denervation met primary/secondary efficacy BP lowering endpoints at 2 months
Key Points: Endovascular ultrasound denervation (uRDN) is a potentially useful technique in…
Amulet IDE: Continued safety and effectiveness of the Amulet LAA occluder device at three years in patients with nonvalvular atrial fibrillation
Key Points: In 2021, the Amulet IDE study demonstrated that the novel…
CLASP IID: The PASCAL system is a safe and beneficial therapy for severe degenerative mitral regurgitation
Key Points: The MitraClip system has been established as a robust platform…
PROTECTED TAVR: No Overall Stroke Reduction With Embolic Protection Devices in TAVR, But Fewer Disabling Strokes
Key Points: Stroke is a feared complication of TAVR. However, the potential…
Radial cath associated with fewer deaths and bleeding: RTC study
Key Points Transradial access has emerged as the preferred initial access method…
Full-dose anticoagulation prevents thrombotic events in COVID patients: COVID-PACT
Key Points Given the increased thrombotic risk in COVID patients, there has…
Coronary Artery Plaque Activity Predicts Recurrent Cardiac Events: results from the PRE-18FFR Trial
Key Points Understanding the future risk of myocardial infarction and death for…
When and How Much Should We lower LDL and Systolic Blood Pressure in Our Patients? Artificial Intelligence and Causal Effects May Provide Answers
Key Points: • Current risk estimating algorithms exclude causal effects and therefore…
It’s Time to Randomize: Smartphone-Based Screening for Atrial Fibrillation – The Siteless, Digital, Randomized eBRAVE-AF Trial
Key Points Wearable technologies based on photoplethysmographic measurements of irregular pulses can…
Artificial Intelligence can improve detection of severe aortic stenosis from echocardiograms: AI-ENHANCED AS shows.
Key Points Aortic stenosis, despite being life-threatening, is often underdiagnosed. It is…
Uncoupling Hemostasis from Thrombosis: Adding Oral FXIa Inhibitor Asundexian to Antiplatelet Therapy After Acute Non-Cardioembolic Stroke – PACIFIC-STROKE
Key Points Selective XIa inhibitor Asundexian may innovate the field of oral…
Uncoupling Hemostasis from Thrombosis: Adding Oral FXIa Inhibitor Asundexian to DAPT After Acute Myocardial Infarction – PACIFIC-AMI.
Key Points Selective XIa inhibitor Asundexian may innovate the field of oral…
Acetazolamide results in improved decongestion, faster: results from ADVOR
Key Points: Residual decongestion after a hospitalization for acute decompensated heart failure…
More Evidence For the Newest Guideline Directed Medical Therapy Pillar – Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (The DELIVER Trial)
Key Points: The use of sodium-glucose cotransporter-2 inhibitor (SGLT2i) in heart failure…
Routine PCI confers no added benefit in severe left ventricular dysfunction: REVIVED
Key Points REVIVED is the first large scale clinical trial to assess…
Sacubitril/Valsartan has no significant effect on cognition: PERSPECTIVE
Key Points There has been a theoretical concern of potential increased amyloid…
Less Structural Valve Deterioration at 5 years with TAVR: Insights from CoreValve/SURTAVI Trials
Key Points: As transcatheter aortic valve replacement (TAVR) has experienced expanded indications…