AI outperforms humans in LVEF assessments: EchoNet-RCT
Despite major advances in the implementation of artificial intelligence (AI) in Cardiology,…
Acetazolamide results in improved decongestion, faster: results from ADVOR
Key Points: Residual decongestion after a hospitalization for acute decompensated heart failure…
More Evidence For the Newest Guideline Directed Medical Therapy Pillar – Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (The DELIVER Trial)
Key Points: The use of sodium-glucose cotransporter-2 inhibitor (SGLT2i) in heart failure…
No improvement with allopurinol for patients with ischemic heart disease: ALL-HEART
Key Points Allopurinol had previously shown an improvement in exercise time and…
Routine PCI confers no added benefit in severe left ventricular dysfunction: REVIVED
Key Points REVIVED is the first large scale clinical trial to assess…
Sacubitril/Valsartan has no significant effect on cognition: PERSPECTIVE
Key Points There has been a theoretical concern of potential increased amyloid…
Treatment with sodium thiosulfate showed no effect on infarct size in STEMI: GIPS IV
Key Points: In the GIPS-IV study, patients with STEMI were randomized to…
Residual inflammation plays important role in risk of MACE for patients already on lipid-lowering medication: CANTOS Substudy
Key Points: In the original CANTOS, patients with stable CAD post-MI with…
Alarmingly Low Rates of Extraction for CIED Infection Despite National and International Recommendations: a Nationwide Observational Study among Over 10,000 Medicare Patients
Key Points Prompt and complete removal of CIED systems is strongly recommended…
Less Structural Valve Deterioration at 5 years with TAVR: Insights from CoreValve/SURTAVI Trials
Key Points: As transcatheter aortic valve replacement (TAVR) has experienced expanded indications…
CLASP-TR demonstrates significant improvement in tricuspid regurgitation up to one year after procedure.
Key Points Tricuspid regurgitation is a debilitating valve disorder characterized by shortness…
The PARTITA Trial: VT Ablation After the First Episode of VT Treated with Shock is Superior to Conservative Treatment Among Patients with Ischemic and Non-Ischemic Cardiomyopathy.
Key Points While VT ablation has been associated with improved survival, the…
Patirometer allows for maintenance of target doses of GDMT in patients with hyerkalemia: DIAMOND trial
Key Points Optimal medical therapy for patients with Heart Failure with Reduced…
Uncoupling Hemostasis from Thrombosis: A Promising Comparison of Oral FXIa Inhibitor Asundexian Versus Apixaban in Patients with Atrial Fibrillation – But More Data Are Needed.
Key Points Selective XIa inhibitor Asundexian may innovate the field of oral…
Alirocumab initiation after MI associated with lower plasma atheroma volume: PACMAN-AMI
Key Points PCSK-9 inhibitors have emerged as a viable treatment option patients…
Mavacamten improves LVOT gradients in patients with HCM: EXPLORER-LTE
Key Points: In the EXPLORER-LTE study, patients with severely symptomatic obstructive HCM…
Vupanorsen shown to effectively decrease non-HDL cholesterol in patients already on statins: TRANSLATE-TIMI 70
Key Points: A need for various lipid-lowering agents to combat high cholesterol…
Reduction in Lp(a) possible with siRNA therapy: APOLLO
Key Points: In the Phase I APOLLO study, patients without known ASCVD…
FAME 3 sub-study shows no difference in quality of life between FFR-guided PCI and CABG.
Key Points PCI has yet to be shown to be superior to…
Effects of Diltiazem on Coronary Vasomotor Dysfunction: EDIT-CMD
Key Points: In the EDIT-CMD study, patients with coronary vasomotor dysfunction (encompassing…