Functional Improvement of non-infarcT relaTed coronary artery stenosis by Extensive LDL-C Reduction with a PCSK9 Antibody (FITTER)
Key Points: Adverse cardiovascular events can still occur from atherosclerotic events in non-culprit coronary arteries Evidence suggests lipid lowering therapy can... Read more.
A Low-Dose Triple Single-Pill Combination Effective at Lowering Blood Pressure
Key Points: A single pill containing low doses of three different medicines induced significant and rapid reductions in blood pressure (BP) vs. dual therapy or placebo,... Read more.
OCCUPI: Optical Coherence Tomography (OCT) Outperforms Conventional Angiography in Guiding Revascularization for Complex Coronary Lesions
Key Points: In all-comer populations, coronary imaging guidance shows superior outcomes compared to conventional angiography in percutaneous coronary interventions... Read more.
EARTH STEMI: Complete Revascularization Reduces Ischemic Events up to 4 years Among Older Patients with STEMI with Multivessel Disease
Key Points: Approximately 50% of patients with STEMI have multivessel disease but data regarding the benefit of complete versus culprit only revascularization are... Read more.
SENIOR-RITA: In Elderly Patients With NSTEMI, An Invasive Strategy Improved Clinical Outcomes Compared To Optimal Medical Therapy Alone
Key Points: Many older patients with NSTEMI do not receive coronary angiography during their index admission due to a high concern for complications and uncertainty... Read more.
Safety and care of no fasting prior to catheterization laboratory procedures: a non-inferiority randomized control trial protocol (SCOFF trial)
KEY POINTS: Fasting before cardiac catheterization is a common practice, however, the evidence supporting its benefit is limited The SCOFF trial demonstrated that... Read more.
GUARD–AF: Wearable ECG Patch Increased the Yield of AF Diagnosis
Key Points: A 14-day heart rhythm monitoring with a wearable patch in primary care increased the diagnostic yield for atrial fibrillation by 52% compared to usual... Read more.
OCEANIC AF – Asundexian is inferior to apixaban for stroke prevention in patients with atrial fibrillation
Key Points: Factor XIa inhibition may reduce stroke risk while causing bleeding. In this phase III trial, asundexian, a factor XIa inhibitor, was associated with... Read more.
Edoxaban Monotherapy Associated with Better Net Clinical Benefit than Edoxaban Plus Single Antiplatelet in Patients with AF and Stable CAD: EPIC-CAD
Key Points: In patients with stable coronary artery disease and atrial fibrillation, multiple society guidelines recommend the use of monotherapy with oral anticoagulants... Read more.
STEEER-AF: A Structured Educational Program for Clinicians Improved Adherence to Guideline Recommendation in AF
Key Points: Adherence to guideline recommendations for AF management is suboptimal. STEEER-AF, the first randomized trial conducted by the ESC, assigned treatment... Read more.