Alberto Castro Molina MD

18 Articles

Tirzepatide Lowers MACE vs Dulaglutide in SURPASS-CVOT Patients With Heart Failure

Key Points In SURPASS-CVOT, tirzepatide was previously shown to be non-inferior to…

Health360x.ai Successfully Implemented Decentralized Clinical Trials in Underserved Populations

Key Points: Health360x.ai is an AI-powered digital health platform designed to scale…

Sodium Zirconium Cyclosilicate Enables MRA Optimization in HFrEF with Hyperkalemia: Insights from the REALIZE-K Trial

Key Points: REALIZE-K trial was a double-blind, placebo-controlled, randomized withdrawal study investigating…

Enhanced Efficiency and Accuracy in Echocardiographic Workflow: Insights from the AI-ECHO RCT

Key Points: AI-ECHO RCT is the first randomized trial to evaluate AI-based…

Acoramidis: Open-Label Extension Data Confirms Sustained Benefits in Transthyretin Cardiac Amyloidosis

Key Points: Sustained Efficacy: Continued improvements in cardiac biomarkers, functional capacity, and…

Improved Accuracy of HF Diagnosis with HFDetect-AI

Key Points: HFDetect-AI significantly improves the accuracy of diagnosing heart failure by…

Pre-Hospital Pulse-Dose Glucocorticoid Did not Reduce Infarct Size in STEMI: PULSE-MI

Key Points: The PULSE-MI trial assessed the effects of pre-hospital pulse-dose glucocorticoid…

SWEDEGRAFT Trial: No Advantage of No-Touch vs Conventional Vein Harvesting in Coronary Artery Bypass Surgery

Key Points: The SWEDEGRAFT study is a prospective, binational multicenter, open-label, registry-based…

IVUS-Guided DES Reduced MACE at 1 year Compared to Angiography-Guided PCI: IVUS-ACS Trial

Key Points: The IVUS-ACS trial  assessed whether the use of intravascular ultrasound…

IVUS -DBC: IVUS-guided drug-coated balloon angioplasty improves primary patency

Key Points: One-year success rates of angioplasty in peripheral artery disease (PAD)…

Recaticimab Effective as Add-On Therapy in Non-Familial Hypercholesterolaemia and Mixed Hyperlipidemia: REMAIN-2 Trial 

Key Points Recaticimab effectiveness demonstrated dosage-dependent response indicating versatility in treatment options.…

Lowering blood pressure significantly reduced dementia risk in people with hypertension in rural China

Key Points: Intensive blood pressure (BP) lowering intervention was tested on hypertensive…

DICTATE-AHF Trial: Early Dapagliflozin in AHF does not meet primary endpoint of diuretic efficiency

Key Points: The DICTATE-AHF trial explored early initiation of the SGLT2 inhibitor…

RIGHT Trial: Anticoagulation shows no benefit after primary PCI in STEMI

Key Points: The RIGHT trial assessed the benefit of post-procedural anticoagulation (PPA)…

FIRE: Complete revascularization better than culprit-only strategy for elderly with MI and MVD

Key Points The FIRE trial aimed to address the lack of evidence…

STREAM-2 Trial: Half-dose TNK + PCI Provides Effective reperfusion In Elderly STEMI Patients

Key Points: Pharmaco-invasive (PI) strategy with half-dose tenecteplase (TNK) is compared to…