EPIC-STEMI: Early Routine PCSK-9 Use Added to High Intensity Statin Reduces LDL after Primary PCI for STEMI
Key Points: Early high-intensity statin therapy is standard of practice in acute…
TIPS-3 Trial: The Combination of Polypill and Aspirin Administered to Patients at Intermediate Risk Led to a Lower Incidence of Cardiovascular Events Compared With Double Placebo
A recent trial by Dr. Salim Yusuf, published in The New England Journal…
REPLACE COVID Trial: Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers Can Be Safely Continued in Patients Admitted to Hospital With COVID-19
A recent trial by Dr. Jordana B Cohen, published in The LANCET, indicated that…
Post-Hoc Analysis of ISCHEMIA Trial: The Choice of Myocardial Infarction Definition Influences Clinical Interpretation of Results
A recent study by Dr. Bernard R. Chaitman, published in Circulation investigated…
DAPA Trial: Prophylactic Defibrillator Implantation After Primary Percutaneous Coronary Intervention Lowers Long Term Mortality in Patients at High Risk of Death
Results of the DAPA trial, published in Circulation: Arrhythmia and Electrophysiology, demonstrated…
PREMIER Trial Shows Incremental Plaque Regression by a Single Lipid Apheresis and Maintained Statin Therapy in ACS Patients Treated With PCI
A recent study by Dr. Banerjee, published in Circulation: Cardiovascular Interventions, demonstrated…
Post Hoc Analyses of GLOBAL LEADERS Trial: Compared with Standard 12-Month Dual Anti-Platelet Therapy, Ticagrelor Monotherapy Reduced the Ischemic and Bleeding Events by up to 8% Following Percutaneous Coronary Intervention
The post hoc analyses of GLOBAL LEADERS study by Dr. Hara, published…
100,000 Patient Meta-Analysis Shows Carotid Intima-Media Thickness Progression Can Be Used as a Surrogate Marker for Cardiovascular Risk
A recent meta-analysis of clinical trials with more than 100,000 patients has…
Meta-Analysis of Randomized Trials Shows Early Aspirin Discontinuation with P2y12 Inhibitor Monotherapy Decreases Risks of Major Bleeding After Percutaneous Coronary Intervention
A recent study by Dr. O’Donoghue, published in Circulation, shows that early aspirin…
SASSICAIA Trial Showed No Difference Between Intensified Prasugrel-Based and Standard Clopidogrel-Based Loading Strategies in Terms of Safety and Efficacy in Patients Undergoing Elective Percutaneous Coronary Intervention
A recent study by Dr. Julinda Mehilli, M.D., published in Circulation journal,…
Post Hoc Analysis of Randomized SCOT-HEART Trial: Coronary Computed Tomography Is More Strongly Associated With 5-Year Coronary Events Compared With Exercise Electrocardiography
The post hoc analysis of the SCOT-HEART trial by Dr. Adamson MBChB,…
A Population-Based Study Showed No Association Between COVID-19-Induced In-Hospital Death and Angiotensin-Converting–Enzyme Inhibitors and Angiotensin-Receptor Blockers Use
A recent study by Dr. Mehra, published in the New England Journal…
Study Shows Patient Self Reports Overestimated And Pharmacy Fills Underestimated Medication Persistence
In an original investigation done by Dr. Alexander C. Fanaroff et al and…
Long-Term Follow-Up of the REDUCE-MVI Trial Showed the Superiority of Ticagrelor Over Prasugrel in Maintenance Therapy of Patients With ST-Segment-Elevation Myocardial Infarction
A recent study by Dr. van der Hoeven, published in the Journal of…
Study Shows Myocardial Perfusion Mapping Using Artificial Intelligence Quantification of Cardiovascular Magnetic Resonance Imaging Provides Prognostic Information in Patients With Suspected Coronary Artery Disease Above Traditional Cardiovascular Risk Factors
A recent study by Dr. Knott, published in Circulation, have shown the…
Trial Showed Implementation of High Sensitivity Cardiac Troponin Assays and Universal Definition of Myocardial Infarction Recommendations in Patients with Suspected Acute Coronary Syndrome Increased Diagnosis Rate Without a Change in Outcomes
A recent study by Dr. Chapman, published in Circulation, showed that implementation…
Type 2 Myocardial Infarction (T2MI) Is Associated With Higher All-Cause Mortality Compared to Type 1 Myocardial Infarction (T1MI)
Raphael et al. showed in a prospective cohort study, published in Circulation,…
SYNTAX III REVOLUTION Trial: Non-invasive CT Scanning as a Potential Alternative to Invasive Coronary Angiography for Treatment Decision-Making in Patients with Complex Coronary Artery Disease
A cross-sectional observational study enrolling 223 patients with 3-vessel coronary artery disease,…
ORION-1: 1-Year Follow-Up Data Affirms 2-dose Regimen Using 300 mg of Inclisiran For Persistent LDL-C Lowering
A randomized, double blind, placebo-controlled, phase II clinical trial studying the effect…
TWILIGHT Trial: Single Anti-Platelet Therapy (SAPT) Using Ticagrelor Reduces Bleeding Risk And Preserves Ischemia Prevention Post-PCI
A randomized, double-blinded, placebo-controlled trial which enrolled 7119 high risk patients with…