Plug-based vascular closure device associated with more complications: CHOICE-CLOSURE
In patients with severe aortic stenosis (AS) undergoing transfemoral transcatheter aortic valve…
Abbreviated DAPT can be safe for patients with high bleeding and ischemic risk: MASTER-DAPT substudy
Key Points: In this pre-specified MASTER DAPT sub-study, patients with high bleeding…
Sweet news for new stent: SUGAR trial finds polymer-free stent non-inferior to ZES in patients with diabetes.
Key Points: Patients with diabetes who undergo PCI are more likely to…
PCI guided by Quantitative Flow Reserve Superior to Standard Angiography: FAVOR III China
Key Points: Quantitative Flow Reserve (QFR) is a non-pressure wire method of…
FAME 3: PCI does not meet noninferiority to CABG in patients with three-vessel disease.
Key Points: All-comers with three vessel disease were randomized to undergo FFR-guided…
Influenza Vaccination after Myocardial Infarction Should Become Standard of Care – Results of the IAMI Trial
Key Points: Prior observational and small randomized studies suggested that influenza vaccine…
When Treating Blood Pressure in Older People – How Low Should We Go? Results from the STEP Study: Intensive vs. Standard Blood Pressure Control Among Older Hypertensive Patients
Key Points: The STEP Study was a multicenter, randomized, controlled trial which…
Amulet IDE: a new left atrial appendage occlusion device enters the market for patients with atrial fibrillation and contraindications to anticoagulation.
Key points: • The Amulet IDE is an open-label clinical trial that…
Salt substitutes decrease rates of stroke, cardiovascular events, and mortality: results from SSaSS
Key Points: The Salt Substitute and Stroke (SSaSS) study compared the effect…
ENVISAGE-TAVI AF shows edoxaban noninferior to VKAs in patients with AFib after TAVR.
Key Points: ENVISAGE-TAVI AF is a large, multinational, randomized-control trial investigate the…
SMART-MI shows Benefits of Cardiac Monitoring after Myocardial Infarction
KEY POINTS: Implantable Cardioverter Defibrillators (ICDs) are indicated for post-myocardial infarction patients…
Empagliflozin does it again: Results from EMPEROR-PRESERVED
Key Points: Patients with chronic heart failure with preserved ejection fraction (HFpEF,…
VICTORIA Trial: Vericiguat Reduces Rates of Cardiovascular Death or Hospitalization Due to Heart Failure in Patients with Heart Failure
The results of the VICTORIA trial were presented at the American College…
ORION-10 and ORION-11: Pooled Analysis of Two Phase 3 Trials Showed Sustained LDL Cholesterol Reduction with Inclisiran in Patients with ASCVD or ASCVD Risk Equivalent
The results of a pooled analysis of the ORION-10 and ORION-11 trials…
COMPLETE Trial OCT Substudy: Non-Culprit Lesions with Vulnerable Plaque Morphology Found In Half of Patients with STEMI and Multivessel Disease
The results of the COMPLETE Optical Coherence Tomography Substudy were presented by…
Interim Results of The EVAPORATE Trial Indicate No Change in Low Attenuation Plaque Volume But A Reduction in Total Plaque Volume Following Treatment with Icosapent Ethyl
The interim results of EVAPORATE trial, a study on the effect of…
Intensive LDL Lowering With a Goal of < 70mg/dl Is Superior to Moderate Lowering for Secondary Prevention of Ischemic Stroke Patients
A randomized parallel-group trial comparing intensive LDL-C lowering to modest lowering for…
GALILEO-4D: Rivaroxaban-Aspirin Based Anti-Thrombotic Therapy Post-TAVR Protects From Valve Leaflet Motion Abnormalities
An expanded analysis of 231 patients from the GALILEO trial comparing rivaroxaban-aspirin…
COAPT: Transcatheter Mitral Valve Repair Is a Cost Effective Treatment In Patients with Heart Failure and Secondary Mitral Valve Regurgitation
New findings from the COAPT study were just published in Circulation and…