First-in-Human Gene Therapy (TN-201) Shows Promising Results in MYBPC3-Associated HCM
Key Takeaways: TN-201, a first-in-class gene therapy, was well tolerated and showed…
Artificial Intelligence Enables Novices to Perform Diagnostic-Quality Echocardiography: HeartFocus Study
Key Takeaways: AI-guided echocardiography enables novice users to obtain diagnostic-quality cardiac images…
Survival After Sudden Cardiac Arrest Improves in Young Athletes, but Racial Disparities Persist
Key Takeaways: Survival from sudden cardiac arrest among young competitive athletes increased…
ALPACA Trial – Lepodisiran Significantly Reduces Lipoprotein(a) in Phase II Trial
Key Points Elevated lipoprotein(a) is associated with incident atherosclerotic cardiovascular disease and…
TRILUMINATE– Transcatheter edge-to-edge repair reduces TR severity and HF Hospitalizations
Key Points The TRILUMINATE Pivotal trial previously reported that transcatheter edge-to-edge repair…
PURSUIT Trial – Dose Dependent Reduction in LDL-C with AZD0780, Oral PCSK9 inhibitor
Key Points The majority of ASCVD patients fail to achieve guideline endorsed…
Comparison Of Angiography-Derived FFR to IVUS in PCI: FLAVOUR II
Key Points: In the FLAVOUR II trial, 1839 patients with angiographically-significant coronary…
No Difference with Mobile Integrated Health vs A Transitions Of Care Coordinator in HF: MIGHTy-Heart
Key Points: In the MIGHT-y Heart Trial, 2,003 patients who were hospitalized…
Electronic Provider Notification Significantly Improved Quality of Care Delivered for Severe AS: DETECT AS
Key Points: In the DETECT AS trial, 285 providers for 939 patients…
Routine Cerebral Embolic Protection Did Not Reduce Incidence of Peri-procedural Stroke in TAVI: BHF PROTECT-TAVI
Key Points: Stroke remains one of the most feared complications of transcatheter…
TAVR with Trilogy System Safe and Effective for Aortic Regurgitation: Updated Results from ALIGN-AR
Key Points: Transcatheter aortic valve replacement for aortic valve disease has largely…
Evolut Low Risk Trial: TAVR Non-inferior to Surgical AR at 5 Years in Low-Risk Patient With Severe AS
Key Points: In the initial Evolut Low Risk Trial, patients with severe…
ALLEPRE: Fully Nursing-Led Heart Health Counseling Program Reduces CV Outcomes After ACS
Key Points Nurses are increasingly responsible for cardiovascular risk management, but randomized…
HERZCHECK: A New Paradigm for Assessing Patients at Risk for Heart Failure
Key Points: Individuals in rural areas have a particularly high prevalence of…
FAIR-HF2 Trial: IV Iron Improves Quality of Life But Not CV Events in Heart Failure
Key Points: Iron deficiency is common in patients with heart failure with…
Pre-Op Digifab Before CABG Prevents Post-Op AKI In Patients At High Risk
KEY POINTS: Ouabain, a cardiac glycoside that is structurally similar to digoxin,…
The EquiOx Study: Pulse Oximeter Performance Varies by Skin Pigment
Key Points: Small retrospective studies of critically ill adults have shown pulse…
Lorundrostat is Effective and Safe in Patients with Uncontrolled Hypertension : ADVANCE-HTN Trial
Key Points: Hypertension (HTN), a major risk factor for cardiovascular disease, remains…
FARES II: PCC Improves Hemostasis and Decreases Transfusions in Adult Cardiac Surgery Patients with Coagulopathy
KEY POINTS: Significant bleeding is a common complication of cardiac surgery. Frozen…
DAPA TAVI: Dapagliflozin Reduced All Cause Death or Worsening HF In Elderly Patients Undergoing TAVI
KEY POINTS: SGLT2 inhibitors reduce admission for heart failure exacerbations. Clinical trials…