Retinal AI Scan Could Help Identify Individuals with Elevated ASCVD Risk
Key Points Cardiovascular prevention often breaks down before treatment ever begins. Many patients at elevated risk never make it to formal risk assessment, leaving... Read more.
Electronic Clinician Notifications Improved Timely Valve Evaluation and Treatment in AS and MR: The ALERT Trial
Key Points Severe aortic stenosis and mitral regurgitation are common, effective valve therapies are available, and yet treatment delays remain routine. ALERT tested... Read more.
ADAPT-CEC Trial: A Hybrid AI + Human Approach Proved Most Accurate
Key Points Behind every major cardiovascular trial is a less visible but decisive process: determining whether a suspected event truly meets the trial’s endpoint... Read more.
Patient-Facing HeartLogic Alerts Lowered Hospitalizations in Heart Failure: The NOTIFY-HF Trial
Key Points Heart failure can worsen long before patients feel it. The challenge has never been detected alone. It has been turning early warning into early action.... Read more.
Enlicitide Shows Durable LDL-C Lowering Through 52 Weeks in CORALreef On-Treatment Analysis
Key Points LDL lowering is only as good as its power to keep LDL low. At ACC.26, investigators presented an on-treatment look at enlicitide that focused less on... Read more.
CHAMPION-AF Trial: LAAOD-WATCHMAN FLX Non-Inferior to NOACs
Key Points For years, left atrial appendage closure has largely been framed as a fallback strategy for patients with atrial fibrillation who cannot remain on long... Read more.
First-in-human Trial of CRISPR Gene-editing ANGPTL3 Safely Lowered Cholesterol and Triglycerides
Key Points: CTX310 is a first-in-class in vivo CRISPR-Cas9 therapy designed to permanently disrupt hepatic ANGPTL3, a gene that regulates lipid metabolism. In the... Read more.
Oral KCl Supplementation Lowers Sodium Load and Blood Pressure in Hypertension: SSTT Trial
Key Points The See Sodium to Treat (SSTT) Trial tested whether isolated oral KCl intake without sodium reduction could lower body Na⁺ content and blood pressure... Read more.
Daily Coffee Lowers AFib Recurrence After Cardioversion: The DECAF Trial
Key Points The Does Eliminating Coffee Avoid Fibrillation (DECAF) trial is the first randomized study to directly test whether coffee consumption influences atrial... Read more.