Rivaroxaban for 18 Months Superior to 6 Months To Prevent Recurrent VTE Events in Cancer Patients with Acute-low PE: ONCO PR
Key Takeaways: The ONCO PE trial demonstrated that an 18-month treatment with…
Promising Cardioprotective Effect of ARNi in High-Risk Cancer Patients Treated with Anthracycline Chemotherapy: SARAH
Key Points: Anthracycline (ANT)-based chemotherapy is a known cancer treatment regimen but…
Semaglutide Improves CV Outcomes in Patients with Prior Coronary Artery Bypass Surgery: Insights from the SELECT Trial
Key Takeaways: In this secondary analysis of the SELECT Trial, semaglutide 2.4…
VALOR-HCM: Mavacamten Reduces Long-Term Need for Septal Reduction Therapy in Symptomatic Obstructive HCM
Key Points: In patients with treatment-refractory symptomatic obstructive hypertrophic cardiomyopathy (HCM), invasive…
FLOW Trial: Renal Benefits of Semaglutide in T2DM Similar Regardless of Baseline CV Risk
Key Points Both chronic kidney disease (CKD) and cardiovascular disease (CVD) are…
Reconditioned Pacemakers Non-Inferior To New Pacemakers in Low- and Middle-Income Countries: Preliminary Results from My Heart Your Heart Trial
Key Points: Many patients in low- and middle-Income countries are unable to…
Linear Ablation Combined with EIVOM Provides Additional Benefit in Rhythm Outcomes for Persistent AF Ablation: PROMPT-AF Trial
Key Points: It is unknown if linear ablation with ethanol infusion of…
Metformin and Aggressive Lifestyle Modifications Reduce AF Fibrillation Symptoms but Not Burden: Results From the TRIM-AF Trial
Key Points: Despite prior data suggesting decrease in metabolic stress may reduce…
SUMMIT Subanalysis: Tirzepatide Reduces Symptom Burden in Patients with Obesity-Related HFpEF
Key Points Patients with heart failure with preserved ejection fraction (HFpEF) and…
In a Hierarchical Composite Outcome, Finerenone Shows Reduction in HF Exacerbations in HFmrEF or HFpEF: FINEARTS
KEY POINTS: Hierarchical analysis prioritizing significant events more effectively traditional composite outcomes,…
Finerenone Raises Potassium but Retains Clinical Benefits with Protocol-directed Surveillance and Dose Adjustment: FINEARTS
KEY POINTS: Finerenone, a non-steroidal mineralocorticoid (MRA), increased serum potassium levels more…
HELIOS-B trial – Vutrisiran Reduces Risk of Outpatient Worsening Heart Failure in ATTR-CM in a subgroup analysis
Key Points: Transthyretin amyloidosis (ATTR-CM) is a fatal disease caused by the…
ARREST-AF: Aggressive Risk Factor Management After AF Ablation Reduces Arrythmia Recurrence at 12 Months
Key Points Observation data has suggested that improving cardiometabolic risk factors after…
SUMMIT CMR: Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related HFpEF
Key Points Obesity-related heart failure with preserved ejection fraction (HFpEF) is associated…
SCAN-MP Study: High Prevalence of Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals with Heart Failure
Key Points ATTR cardiac amyloidosis (ATTR-CA) is frequently diagnosed in older Black…
LAA Closure Associated With Less Bleeds vs. Oral Anticoagulation Post AF Ablation: OPTION
Key Takeaways: The OPTION TRIAL assessed the safety and efficacy of WATCHMAN…
Optimization of GDMT Very Modest but Increased Use of MRAs with Audit and Feedback: PHARM-HF A&F Study
Key Points: Over 6 million people in the US live with heart…
A SUMMIT Analysis: Tirzepatide Reduces End Organ Damage in Patients with Obesity and HFpEF
Key Points SUMMIT, a randomized control trial of tirzepatide versus placebo in…
NUDGE-FLU Pool Analysis: Email Reminders Highlighting CV Benefits of Flu Shots Effective for Increasing Vaccine Uptake Post-MI
Key Points Three prior randomized trials including over two million adults in…
Edoxaban Comparable to Warfarin After Surgical Bioprosthetic Valves Implantation: ENBALV Trial
Key Points: In patients after surgical bioprosthetic valves, it remains unclear if…