SUMMIT: Tirzepatide Improved Renal Function in Patients with HFpEF, Obesity, and CKD
Key Points The SUMMIT randomized control trial demonstrated that tirzepatide significantly reduced…
EKSTROM Trial: Low-dose Colchicine Reduced Total Plaque Volume on CCTA, but Not Low Attenuation Plaque
Key Points The COLCOT trial demonstrated colchicine improved coronary plaque characteristics in…
Dapagliflozin Reduced LVMI in Patients with CKD : DECODE-CKD
Key Points The DECODE-CKD trial investigated the effects of SGLT-2 inhibitor Dapagliflozin…
Benefit from Intensive BP Control Across Frailty Statuses – A Post-Hoc Analysis of ESPRIT trial
Key Points The ESPRIT trial assessed whether the efficacy and safety of…
EARLY TAVR: Delayed TAVR Linked with Increased Risk of Death, Stroke, HF, or HFH Within 2 Years
Key Points: In this sub analysis of the EARLY TAVR trial, the…
Early, Short-Term Use of Rivaroxaban Plus DAPT Significantly Reduces Intracoronary Thrombus
Key Points: In the ARISE-ARMYDA 7 trial, 40 patients who presented with…
Solbinsiran, a Small Interfering RNA Targeting ANGPTL3,Reduced ApoB in Patients with Mixed Dyslipidaemia : PROLONG-ANG3
Key Points: Many patients with ASCVD are on LDL-lowering therapy, but many…
Health360x.ai Successfully Implemented Decentralized Clinical Trials in Underserved Populations
Key Points: Health360x.ai is an AI-powered digital health platform designed to scale…
Coaching Intervention Did Not Increase Physical Function or Cardiac Rehabilitation Participation: MACRO
Key Points: Older adults have higher cardiovascular risk in conjunction with other…
GCVRC: Controlling Hypertension and Stopping Smoking at Midlife Associated With Greatest Gains in Additional Life-years Free of CVD
Key Points Five classic risk factors – HTN, DM, HLD, underweight/obesity, and…
0/1-Hour Algorithm Safe and Effective for Rapid Chest Pain Assessment in the ED: DROP-Asian ACS Trial
Key Takeaways: The 0/1-hour hs-cTn algorithm is safe, non-inferior to usual care,…
Routine Orbital Atherectomy Does Not Improve Outcomes vs Balloon Angioplasty for Severely Calcified Coronary Lesions: ECLIPSE Trial
Key Takeaways: Orbital atherectomy as a routine lesion preparation strategy prior to…
AI QCT Coronary Plaque Features More Predictive in Women: CONFIRM2 Registry
Key Points: Women are underdiagnosed and undertreated for CAD, despite higher prevalence…
AI-Quantitative CT Coronary Plaque Features Indicate Higher Relative CV Risk in Women: CONFIRM2 Registry
Key Takeaways: AI-based quantitative coronary plaque assessments significantly improve risk prediction for…
First-in-Human Gene Therapy (TN-201) Shows Promising Results in MYBPC3-Associated HCM
Key Takeaways: TN-201, a first-in-class gene therapy, was well tolerated and showed…
Artificial Intelligence Enables Novices to Perform Diagnostic-Quality Echocardiography: HeartFocus Study
Key Takeaways: AI-guided echocardiography enables novice users to obtain diagnostic-quality cardiac images…
Survival After Sudden Cardiac Arrest Improves in Young Athletes, but Racial Disparities Persist
Key Takeaways: Survival from sudden cardiac arrest among young competitive athletes increased…
ALPACA Trial – Lepodisiran Significantly Reduces Lipoprotein(a) in Phase II Trial
Key Points Elevated lipoprotein(a) is associated with incident atherosclerotic cardiovascular disease and…
TRILUMINATE– Transcatheter edge-to-edge repair reduces TR severity and HF Hospitalizations
Key Points The TRILUMINATE Pivotal trial previously reported that transcatheter edge-to-edge repair…
PURSUIT Trial – Dose Dependent Reduction in LDL-C with AZD0780, Oral PCSK9 inhibitor
Key Points The majority of ASCVD patients fail to achieve guideline endorsed…