OPTION –Indobufen is Noninferior to Aspirin After Coronary Drug-Eluting Stent Implantation
Key Points: Indobufen, a platelet aggregation inhibitor, has been shown to be…
PRECISE–A precision diagnostic strategy in patients with suspected CAD improves outcomes
Key Points: There is substantial heterogeneity in the use of different non-invasive…
RAPCO: Radial artery grafting is superior to both RITA and SVG in patients undergoing CABG
Key Points: Recent guidelines have supported the use of arterial grafts over…
CTS-AMI: Tongxinluo (TXL) improves CV outcomes in acute STEMI
Key Points: Tongxinluo (TXL) is a traditional Chinese medicine with endothelial-protective effects…
PROMINENT: Pemafibrate reduces triglyceride levels but not cardiovascular events in patients with dyslipidemia and T2DM
Key Points High triglyceride levels are associated with increased cardiovascular risk, but…
EPIC-STEMI: Early Routine PCSK-9 Use Added to High Intensity Statin Reduces LDL after Primary PCI for STEMI
Key Points: Early high-intensity statin therapy is standard of practice in acute…
Extended outcomes of BEST: No difference in MACE between PCI and CABG in MVD at 12 years, but higher repeat revascularization and spontaneous MI in PCI arm
Key Points: Previous studies have demonstrated the superiority of CABG over PCI…
Additional background and insight
Presented by Dr. Schuyler Jones, assistant professor of medicine, Duke University, and…
DAPT with Clopidogrel Superior to Ticagrelor one month after PCI: Results from the TALOS-AMI Trial
With the widespread use of second-generation drug eluting stents, it has become…
Aspirin Dosing: a Patient-Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE) trial
KEY POINTS: There was no significant difference in primary composite endpoint of…
PURE Study Finds That Cardiovascular Disease Mortality Is Associated with the Glycemic Index of Foods in the Diet
A recent study by Dr. David J. A. Jenkins, published in the New…
TIPS-3 Trial: The Combination of Polypill and Aspirin Administered to Patients at Intermediate Risk Led to a Lower Incidence of Cardiovascular Events Compared With Double Placebo
A recent trial by Dr. Salim Yusuf, published in The New England Journal…
Post-Hoc Analysis of ISCHEMIA Trial: The Choice of Myocardial Infarction Definition Influences Clinical Interpretation of Results
A recent study by Dr. Bernard R. Chaitman, published in Circulation investigated…
DAPA Trial: Prophylactic Defibrillator Implantation After Primary Percutaneous Coronary Intervention Lowers Long Term Mortality in Patients at High Risk of Death
Results of the DAPA trial, published in Circulation: Arrhythmia and Electrophysiology, demonstrated…
COACT Trial Shows Immediate Coronary Angiography Does Not Change the 1-Year Clinical Outcomes of Patients After Cardiac Arrest Without ST-Segment Elevation
A trial by Dr. Jorrit S. Lemkes, published in JAMA Cardiology, demonstrated…
Study Shows the Efficacy of Adding Corticosteroids to Initial Intravenous Immunoglobulin Therapy in the Prevention of Coronary Artery Abnormality Among Patients at High Risk for Kawasaki Disease
A recent study by Dr. Ryusuke Ae, published in the Journal of…
PREMIER Trial Shows Incremental Plaque Regression by a Single Lipid Apheresis and Maintained Statin Therapy in ACS Patients Treated With PCI
A recent study by Dr. Banerjee, published in Circulation: Cardiovascular Interventions, demonstrated…
Post Hoc Analyses of GLOBAL LEADERS Trial: Compared with Standard 12-Month Dual Anti-Platelet Therapy, Ticagrelor Monotherapy Reduced the Ischemic and Bleeding Events by up to 8% Following Percutaneous Coronary Intervention
The post hoc analyses of GLOBAL LEADERS study by Dr. Hara, published…
DAPA-HF Trial: Compared to Placebo, Dapagliflozin Was Beneficial in Patients with Heart Failure and Reduced Ejection Fraction Regardless of Background Diuretic Therapy
A recent study by Dr. Alice M. Jackson M.D., published in Circulation…
Meta-Analysis of Randomized Trials Shows Early Aspirin Discontinuation with P2y12 Inhibitor Monotherapy Decreases Risks of Major Bleeding After Percutaneous Coronary Intervention
A recent study by Dr. O’Donoghue, published in Circulation, shows that early aspirin…