SUMMIT CMR: Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related HFpEF
Key Points Obesity-related heart failure with preserved ejection fraction (HFpEF) is associated…
SCAN-MP Study: High Prevalence of Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals with Heart Failure
Key Points ATTR cardiac amyloidosis (ATTR-CA) is frequently diagnosed in older Black…
LAA Closure Associated With Less Bleeds vs. Oral Anticoagulation Post AF Ablation: OPTION
Key Takeaways: The OPTION TRIAL assessed the safety and efficacy of WATCHMAN…
Optimization of GDMT Very Modest but Increased Use of MRAs with Audit and Feedback: PHARM-HF A&F Study
Key Points: Over 6 million people in the US live with heart…
A SUMMIT Analysis: Tirzepatide Reduces End Organ Damage in Patients with Obesity and HFpEF
Key Points SUMMIT, a randomized control trial of tirzepatide versus placebo in…
NUDGE-FLU Pool Analysis: Email Reminders Highlighting CV Benefits of Flu Shots Effective for Increasing Vaccine Uptake Post-MI
Key Points Three prior randomized trials including over two million adults in…
Edoxaban Comparable to Warfarin After Surgical Bioprosthetic Valves Implantation: ENBALV Trial
Key Points: In patients after surgical bioprosthetic valves, it remains unclear if…
PanEcho: AI-Based Automated Image Analysis Improved Quality and Efficiency in Echocardiography
Key Points: Transthoracic echocardiography is foundational to diagnosis and evaluation of myriad…
TOPSPIN- A: Three-Combination of Antihypertensive Meds Provided Similar BP Control
Key Points: The global burden of hypertension (HTN) with high globally at…
Personalized App-Based Coaching Improved Physical Activity in HFpEF Patients (MyoMobile Study)
Key Points: Though physical inactivity leads to poor cardiovascular outcomes, especially for…
ZODIAC: A Risk-based Decision Support System Did Not Significantly Improve Lipid-Lowering vs Usual Care
Key Points Maximizing lipid lowering therapy (LLTs) to optimize residual cardiovascular disease…
Exenatide, a GLP-1 Analog, Did Not Reduce Organ Injury, Stroke or Death During Cardiac Surgery: GLORIOUS Trial
KEY POINTS: Exenatide is a glucaon-like-peptide-1 agonist (GLP-1) improves glycemic control, and…
Plozasiran Showed Sustained Reductions in TG in Familial Chylomicronemia Syndrome: PALISADE Trial
Key Points: Familial chylomicronemia syndrome (FCS) is characterized by extremely high plasma…
Catheter Ablation Better Than Antiarrhythmic Drugs for VT in Ischemic Cardiomyopathy With ICD: VANISH2 Trial
Key Takeaways: The VANISH2 trial compared catheter ablation with systematic antiarrhythmic drug…
CLEAR SYNERGY: No Benefit with Routine Spironolactone in MI Patients
Key Takeaways: The CLEAR SYNERGY trial was a multicenter trial with a…
CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran Associated with Durable Reductions in Serum TTR levels for ATTR -CM
Key Takeaways: A single dose of nexiguran ziclumeran (nex-z), a CRISPR-Cas9-based therapy,…
SUMMIT: Tirzepatide Decreased The Risk Of Worsening HF And CV Death in HFpEF + Obesity
Key Points SUMMIT was a multi-national trial that compared cardiovascular outcomes among…
BPROAD: Intensive Blood Pressure Target Reduces MACE in Type 2 Diabetes
Key Points BPROAD was a randomized control trial in China that assigned…
Rivaroxaban Did Not Reduce Cognitive Decline and Stroke/TIA in Young AF Patients: BRAIN-AF Trial
Key Points: In patients with atrial fibrillation, it remains unclear if anticoagulation…
QFR Did Not Meet Non-inferiority to FFR: FAVOR III Europe Trial
The FAVOR III Europe study aimed to investigate whether a QFR-based diagnostic…