Edoxaban Monotherapy Associated with Better Net Clinical Benefit than Edoxaban Plus Single Antiplatelet in Patients with AF and Stable CAD: EPIC-CAD
Key Points: In patients with stable coronary artery disease and atrial fibrillation,…
STEEER-AF: A Structured Educational Program for Clinicians Improved Adherence to Guideline Recommendation in AF
Key Points: Adherence to guideline recommendations for AF management is suboptimal. STEEER-AF,…
IVORY FINALE: Low-Dose IL-2 Reduces Arterial Inflammation after ACS
Key Points: While inflammation is critical to the pathogenesis of atherosclerosis, few…
QUADRO – Quadruple Polypill More Effective In Lowering Blood Pressure Than Taking Three Separate Medications in Resistant Hypertension
Key Points: Treatment of resistant hypertension often involves at least three or…
A Single Combined Measure Of hsCRP, LDL-C, And Lp(A) Predicts Incident CV Events Over 30 Years Among Women’s Health Study Participants
Key Points: While drug trials evaluate the short-term cardiovascular risk associated with…
ASSURE DES: No Difference In Ischemic Events If Aspirin Is Interrupted Or Continued In Patients With DES Undergoing Non-Cardiac Surgery
Key Points: Anti-platelet therapy after coronary drug eluting stent (DES) placement reduces…
Morning vs. evening dosing of blood pressure meds: No differences in outcomes or safety for either community-dwelling adults or frail nursing home residents
Key Points: Blood pressure follows a circadian rhythm, peaking after waking and…
NOTION-3: Revascularization in Patients Undergoing TAVI Associated with Lower Risk of MACE vs Conservative Treatment
Key Points: The NOTION-3 trial found that FFR-guided revascularization with PCI in…
TAVI Superior to Surgical Aortic Valve Replacement in Women: RHEIA Trial
Key Points: The RHEIA trial found that TAVI was superior to surgical…
SWEDEGRAFT Trial: No Advantage of No-Touch vs Conventional Vein Harvesting in Coronary Artery Bypass Surgery
Key Points: The SWEDEGRAFT study is a prospective, binational multicenter, open-label, registry-based…
Transcatheter Mitral-valve Repair Lowers Hospitalization or CV Death vs Medical Therapy Alone in HF with Moderate to Severe MR: RESHAPE-HF2 Trial
Key Points: The Mitral Transcatheter Edge-to-Edge Repair (M-TEER) procedure with the MitraClip…
Continuation of Anticoagulation Non-Inferior to Interruption during TAVI: POPular PAUSE TAVI Trial.
Key Points: Many patients who undergo transcatheter aortic-valve implantation (TAVI) have an…
Pooled Analysis Showed Semaglutide Reduced Combined CV death or Worsening HF and Worsening HF alone but No Significant Effect on CV Death
Key Points: Heart failure with mildly reduced or preserved ejection fraction (hereafter…
Transcatheter Edge-To-Edge Repair Is Non-Inferior To Surgery In Patients With Secondary Mitral Regurgitation: MATTERHORN Trial
Key Points: The MATTERHORN trial found that the transcatheter edge-to-edge repair (TEER)…
T-TEER Significantly Reduced the Severity of Secondary Tricuspid Regurgitation and Improved Quality of Life. TRI-FR Trial
Key Points: The TRI.FR trial found that tricuspid transcatheter edge-to-edge repair (T-TEER)…
ABYSS – Beta Blocker Interruption in Post-Myocardial Infarction Patients
Key Points: In the ABYSS trial, 3700 patients who had a left…
Vitrusiran Reduces Risk of Death and CV Events in Patients with ATTR-CM
Key Points: ATTR amyloid cardiomyopathy, resulting from accumulation of TTR amyloid protein…
Consistent Renal Benefits of Semaglutide in CKD and T2DM Patients With or Without SGLT2 Inhibitors Use. FLOW Trial
The FLOW trial showed that among patients with chronic kidney disease (CKD)…
Tirzepatide Reduced Apnea-hypopnea Index and Weight in Obese Patients with Moderate Sleep Apnea: SURMOUNT-OSA Trials
Obstructive sleep apnea is associated with cardiovascular complications and is seen more…
LENS Trial: Fenofibrate Significantly Reduced Progression of Diabetic Retinopathy vs Placebo.
- Findings from cardiovascular trials suggested that fenofibrate therapy may reduce the…