RELIEVE HF: Inter-Atrial Shunting Does Not Reduce Symptoms or Improve Prognosis in HF
Key Points: Inter-atrial shunting (IAS) may provide a useful opportunity to dynamically…
SHASTA 2: Novel RNAi Therapeutic Plozasiran Results in Sustained Reduction In Triglycerides in Severe Hypertriglyceridemia
Key Points: Severe hypertriglyceridemia portends high risk of both CVD and acute…
DanGer Shock: Impella Reduces All-Cause Mortality in STEMI Cardiogenic Shock
Key Points: Cardiogenic shock (CS) mortality remains high despite increased utilization of…
AT-001, a potent aldose reductase inhibitor, did not improve exercise capacity in diabetic cardiomyopathy with impaired exercise capacity
Key Points: The ARISE-HF trial evaluates the use of AT-001, a potent…
TAVR non-inferior to SAVR in Low to Intermediate Risk Patients With Severe Aortic Stenosis: DEDICATE-DZHK6 Trial
Key Points In the DEDICATE-DZHK6 trial, patients with a history of severe…
ORBITA COSMIC: Coronary sinus reducer did not improve transmural myocardial perfusion but angina symptoms
Key Points - Coronary sinus reduction (CSR) is a potential therapeutic device…
TARGET BP I: Alcohol-mediated renal artery denervation reduced SBP in treatment-resistant hypertension at 3 months compared to sham control
Key Points: Achieving hypertension control has remained an elusive goal in the…
Hózhó: Phone-based GDMT Initiation and Uptitration Feasible and Effective among HFrEF patients in Navajo Nation
Key Points: GDMT utilization is suboptimal among American Indian patients with HFrEF…
HUDDLE: Cross-sectional study finds large gap between hypertension prevalence and awareness among former NFL athletes
Key Points: Little is known about the prevalence of cardiovascular risk factors…
Health 360x: Medical assistants more likely to complete training and remain in clinical research in community practices
Key Points: Research coordinators embedded in community-based practices can help ensure that…
HeLP: Behavioral interventions improve cardiac rehabilitation attendance among recently hospitalized patients with lower SES
Key Points: Low-SES patients are less likely to attend CR following hospitalization…
MINT subgroup analysis: Among patients with acute MI and anemia, a restrictive transfusion strategy was associated with higher rates of death and MI at 30 days
Key Points: The MINT trial found that among patients with acute MI…
Routine Assessment of Patient-Reported Health Status in Academic Clinics Did Not Improve Patient-Reported Health-Status: The PRO-HF Trial
Key Points: The latest AHA/ACC Heart Failure (HF) guidelines recommend routine assessment…
A Spirituality-Based Intervention Improves Blood Pressure Control and Central Hemodynamics: The FEEL Trial
Key Points: HTN is a leading cause of cardiovascular (CV) morbidity and…
Advancing Acute MI Care in Densely Populated LMICs: Innovative Standalone Chest Pain Units for Expedited Triage and Timely Management – A Role Model for Global Healthcare Systems
Key Points: The burden of coronary artery disease (CAD) is high in…
Simultaneous Team-Based Remote Education and Medication Titration Increases Diabetes Medication Prescription Compared to a Sequential Approach: The Diabetes Remote Intervention to ImproVe Use of Evidence-based Medications (DRIVE) Study
Key Points: Despite demonstrated effectiveness of many SGLT2-inhibitors and GLP-1 agonists at…
No Benefit of Long-Term Beta-Blockers after MI with Preserved EF: REDUCE AMI Trial
Key Points -Beta blocker therapy in patients with acute MI is the…
TACT2: Chelation therapy with EDTA does not improve cardiovascular outcomes in post-MI patients with diabetes
Key Points: EDTA is a highly effective chelator of the ubiquitous pollutants…
ULTIMATE-DAPT: De-escalating to ticagrelor alone after 1 month reduced bleeding without an increase in ischemic events compared to continuous DAPT through 1 year
Key Points: The optimal time to de-escalate from DAPT to SAPT following…
LIBerate-HR Trial: Lerodalcibep, A Small-Binding Protein Based PCSK9 Inhibitor Administered Monthly Significantly Lowered LDL-C
Key Points - Newer cholesterol guidelines advise lower target values for LDL-C…