New Study Sets the Stage for Determining Optimal Antithrombotic Regimen in TAVR Patients
According to a study published in JACC: Cardiovascular Interventions, sex, renal failure, and atrial fibrillation affected mortality the most at 3-year follow-up following transcatheter aortic valve replacement (TAVR). In contrast,…
Effects of Maternal Obesity On Cardiac Development
The results of a fascinating study conducted by Dr. Patricia Iozzo and her colleagues at the Institute of Clinical Physiology, in Pisa, Italy showed that neonatal changes in cardiac morphology…
Adjunctive Low Dose Alteplase During Primary PCI Fails to Imrpove Microvascular Obstruction in STEMI Patients
A multi-center randomized, double blind, placebo-controlled, parallel group clinical trial has shown that among patients with acute ST-elevation myocardial infarction (STEMI) presenting within 6 hours of symptoms, adjunctive low-dose intracoronary…
Is High Educational Attainment Associated With Higher Cardiovascular Risk and Mortality in Hispanic Individuals?
Results from a study conducted by investigators at Stanford University School of Medicine did not support the Hispanic paradox in a highly educated Hispanic population. The study demonstrated that Hispanic…
Use of Dynamic Myocardial Imaging in the Evaluation of Heart Failure With Preserved Ejection Fraction Provides Prognostic Value
A study published in JACC: Cardiovascular Imaging has shown that both left ventricular systolic and diastolic reserves contribute to risk prediction in Heart Failure With Preserved Ejection Fraction (HFpEF). Therefore, the…
Prior Cerebrovascular Disease: A Key Factor In The Assessment for Optimal Left Main Coronary Artery Revascularization Strategy
A study conducted by Dr. Gregg W.Stone and his colleagues from Columbia University Medical Center demonstrated that patients with left main coronary artery disease (LMCAD) and prior cerebrovascular disease (CEVD)…
Survival Over the First Few Decades Following Tetralogy of Fallot Repair
A study published in JAMA cardiology has shown that long-term survival after simple Tetralogy of Fallot (TOF) repair is excellent. Staged repair and non–valve-sparing operations were negatively associated with survival…
CHIPping Away at the Pathogenesis of Chronic Heart Failure: What is the Clinical Significance of Clonal Hematopoiesis of Indeterminate Potential (CHIP)?
In a study published in JAMA cardiology, the data suggested that somatic mutations in hematopoietic cells, specifically in the most commonly mutated CHIP driver genes TET2 and DNMT3A, could be…
2018: Cardiology News at A Glance
COAPT trial This prospective, multicenter, open-label, randomized trial aimed to assess the use of transcatheter mitral valve repair in heart failure (HF) patients with mitral regurgitation due to left ventricular…
ILLUMENATE European RCT Demonstrates Durability of Low-Dose DCB in Humans For the First Time
The two-year results of the ILLUMENATE European randomized clinical trial conducted by Brodmann and her colleagues have displayed a sustained treatment effect with a low-dose drug-coated balloon (DCB) with an…
Novel Target for STEMI Patients: Cholesterol Efflux Capacity Inversely Associated with All-Cause Mortality
A population-based cohort study has shown that patients with a higher serum cholesterol efflux capacity, the capacity of HDL particles to mediate cholesterol efflux from macrophages, have a marked decrease…
Major Bleeding Rates With Antithrombotic Therapy in Atrial Fibrillation
The results of a study conducted by Rein et al. have shown that patients with atrial fibrillation on triple therapy experienced high rates of major bleeding compared with patients on dual…
Lifetime Stroke Risk From Age Twenty Five Onwards Is Approximately One-Fourth and Varies Geographically, According to A New Study
A study conducted by the GBD 2016 Lifetime Risk of Stroke Collaborators demonstrated that the global lifetime risk of stroke from the age of 25 years onward was approximately 25%…
Coronary Artery Calcium Scoring: A Screening Tool For Statin Prescription In the Primary Prevention of Cardiovascular Disease?
According to a new study published in the Journal of American College of Cardiology, patients with higher coronary artery calcium (CAC) scores were more likely to achieve benefit from statins…
Long-Term Risk of Death Shows Dramatic Increase Following Femoropopliteal Application of Paclitaxel-Coated Balloons and Stents
The results of a systematic review and meta-analysis of randomized controlled trials conducted by Konstantinos Katsanos and his colleagues have showcased an increased risk of death following application of paclitaxel-coated…
‘CONSERVE’ Your Energy and Resources: Selective Referral Strategy Using CCTA Non-Inferior to Direct Referral Strategy to ICA for Suspected CAD
The findings of a randomized, controlled, open-label trial conducted by Dr. Hyuk-Jae Chang, Division of Cardiology, Severance Cardiovascular Hospital, Seoul, South Korea and his colleagues, has reported that in stable…
Does One Need A Parachute While Jumping From An Aircraft? A Clinical Trial Addresses the Question
Parachute use on jumping from an aircraft does not reduce death or major traumatic injuries when compared with jumping with empty backpacks, according to a new trial published in the British…
ICU Stethoscopes Foster DNA from Nosocomial Bacteria
A molecular analysis of bacterial contamination on stethoscopes in an intensive care unit conducted by Vincent R. Knecht and his colleagues at University of Pennsylvania Perelman School of Medicine, Philadelphia,…
Flu Shot Linked to Heart Failure Survival
Patients with heart failure (HF) who receive influenza vaccination may be at a lower risk of both all-cause mortality and cardiovascular death after adjustment for confounders, according to a large-scale…