Solbinsiran, a Small Interfering RNA Targeting ANGPTL3,Reduced ApoB in Patients with Mixed Dyslipidaemia : PROLONG-ANG3
Key Points: Many patients with ASCVD are on LDL-lowering therapy, but many…
Health360x.ai Successfully Implemented Decentralized Clinical Trials in Underserved Populations
Key Points: Health360x.ai is an AI-powered digital health platform designed to scale…
Coaching Intervention Did Not Increase Physical Function or Cardiac Rehabilitation Participation: MACRO
Key Points: Older adults have higher cardiovascular risk in conjunction with other…
GCVRC: Controlling Hypertension and Stopping Smoking at Midlife Associated With Greatest Gains in Additional Life-years Free of CVD
Key Points Five classic risk factors – HTN, DM, HLD, underweight/obesity, and…
0/1-Hour Algorithm Safe and Effective for Rapid Chest Pain Assessment in the ED: DROP-Asian ACS Trial
Key Takeaways: The 0/1-hour hs-cTn algorithm is safe, non-inferior to usual care,…
Routine Orbital Atherectomy Does Not Improve Outcomes vs Balloon Angioplasty for Severely Calcified Coronary Lesions: ECLIPSE Trial
Key Takeaways: Orbital atherectomy as a routine lesion preparation strategy prior to…
AI QCT Coronary Plaque Features More Predictive in Women: CONFIRM2 Registry
Key Points: Women are underdiagnosed and undertreated for CAD, despite higher prevalence…
AI-Quantitative CT Coronary Plaque Features Indicate Higher Relative CV Risk in Women: CONFIRM2 Registry
Key Takeaways: AI-based quantitative coronary plaque assessments significantly improve risk prediction for…
First-in-Human Gene Therapy (TN-201) Shows Promising Results in MYBPC3-Associated HCM
Key Takeaways: TN-201, a first-in-class gene therapy, was well tolerated and showed…
Artificial Intelligence Enables Novices to Perform Diagnostic-Quality Echocardiography: HeartFocus Study
Key Takeaways: AI-guided echocardiography enables novice users to obtain diagnostic-quality cardiac images…
Survival After Sudden Cardiac Arrest Improves in Young Athletes, but Racial Disparities Persist
Key Takeaways: Survival from sudden cardiac arrest among young competitive athletes increased…
ALPACA Trial – Lepodisiran Significantly Reduces Lipoprotein(a) in Phase II Trial
Key Points Elevated lipoprotein(a) is associated with incident atherosclerotic cardiovascular disease and…
TRILUMINATE– Transcatheter edge-to-edge repair reduces TR severity and HF Hospitalizations
Key Points The TRILUMINATE Pivotal trial previously reported that transcatheter edge-to-edge repair…
PURSUIT Trial – Dose Dependent Reduction in LDL-C with AZD0780, Oral PCSK9 inhibitor
Key Points The majority of ASCVD patients fail to achieve guideline endorsed…
Comparison Of Angiography-Derived FFR to IVUS in PCI: FLAVOUR II
Key Points: In the FLAVOUR II trial, 1839 patients with angiographically-significant coronary…
No Difference with Mobile Integrated Health vs A Transitions Of Care Coordinator in HF: MIGHTy-Heart
Key Points: In the MIGHT-y Heart Trial, 2,003 patients who were hospitalized…
Electronic Provider Notification Significantly Improved Quality of Care Delivered for Severe AS: DETECT AS
Key Points: In the DETECT AS trial, 285 providers for 939 patients…
Routine Cerebral Embolic Protection Did Not Reduce Incidence of Peri-procedural Stroke in TAVI: BHF PROTECT-TAVI
Key Points: Stroke remains one of the most feared complications of transcatheter…
TAVR with Trilogy System Safe and Effective for Aortic Regurgitation: Updated Results from ALIGN-AR
Key Points: Transcatheter aortic valve replacement for aortic valve disease has largely…
Evolut Low Risk Trial: TAVR Non-inferior to Surgical AR at 5 Years in Low-Risk Patient With Severe AS
Key Points: In the initial Evolut Low Risk Trial, patients with severe…