FAIR-HF2 Trial: IV Iron Improves Quality of Life But Not CV Events in Heart Failure
Key Points: Iron deficiency is common in patients with heart failure with…
Pre-Op Digifab Before CABG Prevents Post-Op AKI In Patients At High Risk
KEY POINTS: Ouabain, a cardiac glycoside that is structurally similar to digoxin,…
The EquiOx Study: Pulse Oximeter Performance Varies by Skin Pigment
Key Points: Small retrospective studies of critically ill adults have shown pulse…
Lorundrostat is Effective and Safe in Patients with Uncontrolled Hypertension : ADVANCE-HTN Trial
Key Points: Hypertension (HTN), a major risk factor for cardiovascular disease, remains…
FARES II: PCC Improves Hemostasis and Decreases Transfusions in Adult Cardiac Surgery Patients with Coagulopathy
KEY POINTS: Significant bleeding is a common complication of cardiac surgery. Frozen…
DAPA TAVI: Dapagliflozin Reduced All Cause Death or Worsening HF In Elderly Patients Undergoing TAVI
KEY POINTS: SGLT2 inhibitors reduce admission for heart failure exacerbations. Clinical trials…
HOST-BR: 3 Months Of DAPT Might be Reasonable For Both Low- And High-Bleeding Risk Patients After PCI With DES
Key Points After DES placement, guidelines recommend considering shorter DAPT duration (e.g.…
SOUL: Oral Semaglutide Reduced CV Events In High-Risk Patients With T2DM with ASCVD or CKD
Key Points Injectable semaglutide, a GLP-1 receptor agonist, reduces CV events in…
Bentracimab Significantly Restored Platelet Function in Patients Taking Ticagrelor and Undergoing Urgent Surgery
Key Points: A major limitation of antithrombotic therapy is the risk of…
Semaglutide Increased Walking Distance in Patients with T2DM and Symptomatic PAD
Key Points: Patients with peripheral artery disease (PAD) in combination with type…
API-CAT Trial: Extended Reduced-Dose Apixaban Non-Inferior to Full Dose for VTE in Cancer
Key Points: Venous thromboembolism (VTE) is a leading cause of mortality in…
WARRIOR Trial: Intensive Medical Therapy Didn’t Lower Events in INOCA vs Usual Care
Key Points: In the WARRIOR trial, ~ 2500 women with signs and…
RIVAWAR Trial: Rivaroxaban Is Comparable to Warfarin for Post-MI Left Ventricular Thrombus
Key Points: Left ventricular thrombus (LVT) is a serious complication following heart…
Sodium Zirconium Cyclosilicate Enables MRA Optimization in HFrEF with Hyperkalemia: Insights from the REALIZE-K Trial
Key Points: REALIZE-K trial was a double-blind, placebo-controlled, randomized withdrawal study investigating…
Enhanced Efficiency and Accuracy in Echocardiographic Workflow: Insights from the AI-ECHO RCT
Key Points: AI-ECHO RCT is the first randomized trial to evaluate AI-based…
Obicetrapib Demonstrates Promising Lipid-Lowering Efficacy and Safety in Heterozygous Familial Hypercholesterolemia: BROOKLYN
Key Points: BROOKLYN was a phase III trial that assessed the safety…
Acoramidis: Open-Label Extension Data Confirms Sustained Benefits in Transthyretin Cardiac Amyloidosis
Key Points: Sustained Efficacy: Continued improvements in cardiac biomarkers, functional capacity, and…
Geographic Variations in Racial Disparities for Peripheral Artery Disease Treatment in the U.S.
Key Takeaways: Black patients with peripheral artery disease (PAD) had significantly higher…
Mitral Annular Calcification Severity Predicts Outcomes in Severe Aortic Stenosis Patients Undergoing TAVR
Key Points: The presence of mitral annular calcification (MAC) in prior studies…
Impact of Technology-Enabled Home-Based Cardiac Rehabilitation on Functional Status and Cardiovascular Health Metrics: mTECH-Rehab Trial
Key Points: Cardiac rehabilitation (CR) is a guideline-directed multifaceted intervention that is…