Study Shows Heart Transplants From Hepatitis C Positive Donors Safe; Potential for Expanding Donor Pool and Shortening Wait-Times
In an observational case series of 80 patients who underwent heart transplant…
SYNTAX III REVOLUTION Trial: Non-invasive CT Scanning as a Potential Alternative to Invasive Coronary Angiography for Treatment Decision-Making in Patients with Complex Coronary Artery Disease
A cross-sectional observational study enrolling 223 patients with 3-vessel coronary artery disease,…
Intensive LDL Lowering With a Goal of < 70mg/dl Is Superior to Moderate Lowering for Secondary Prevention of Ischemic Stroke Patients
A randomized parallel-group trial comparing intensive LDL-C lowering to modest lowering for…
GALILEO-4D: Rivaroxaban-Aspirin Based Anti-Thrombotic Therapy Post-TAVR Protects From Valve Leaflet Motion Abnormalities
An expanded analysis of 231 patients from the GALILEO trial comparing rivaroxaban-aspirin…
Enhanced Vasospasm And Reduced Vasodilator Function Linked To Worse Outcomes In Patients With Non-Obstructive Coronary Arteries
A single center study that included 187 patients who presented with angina-like…
New-Onset AF After TAVR linked To Worse Long-Term Outcomes Compared With Patients With Pre-Existing AF and No AF
A registry-based cohort study including 72,660 Medicare patients with and without atrial…
ORION-1: 1-Year Follow-Up Data Affirms 2-dose Regimen Using 300 mg of Inclisiran For Persistent LDL-C Lowering
A randomized, double blind, placebo-controlled, phase II clinical trial studying the effect…
TWILIGHT Trial: Single Anti-Platelet Therapy (SAPT) Using Ticagrelor Reduces Bleeding Risk And Preserves Ischemia Prevention Post-PCI
A randomized, double-blinded, placebo-controlled trial which enrolled 7119 high risk patients with…
Dual Anti-thrombotic Therapy Safe For Patients with Atrial Fibrillation and Recent PCI:ENTRUST-AF PCI
Results from a phase-IIIb, open-label, multi-center, randomized clinical trial comparing the safety…
Transcranial Ultrasound Used As an Adjunct to tPA Fails To Improve Functionality in Ischemic Stroke Patients
A randomized, mutilcenter, placebo-controlled, phase 3 clinical trial which enrolled 676 patients…
TAVR Using Balloon Expandable Valve Superior To Surgical Aortic Valve Replacement In Low Risk Patients With Severe Aortic Valve Stenosis
A randomized multi-center trial which enrolled 1000 patients from 71 centers around…
U.S. Food and Drug Administration (FDA) Continues To Investigate Recall of Contaminated Blood Pressure Medication
The US food and drug Administration (FDA) has recently been conducting an…
Adjunctive Low Dose Alteplase During Primary PCI Fails to Imrpove Microvascular Obstruction in STEMI Patients
A multi-center randomized, double blind, placebo-controlled, parallel group clinical trial has shown…
Novel Target for STEMI Patients: Cholesterol Efflux Capacity Inversely Associated with All-Cause Mortality
A population-based cohort study has shown that patients with a higher serum…
NT-ProBNP-Guided Medical Therapy Failed To Show Superiority Compared To Usual Care In HFrEF
Results of a multi-center, randomized clinical trial which enrolled 894 patients with…
Superior Efficacy of Sacubitril-Valsartan Compared to Enalapril for lowering NT Pro-BNP in Patients Hospitalized for HFrEF
Results from a multi-center, randomized, double-blind, double dummy, parallel group clinical trial…
Deciphering the Underpinnings of MINOCA (MI with Non-Obstructive Coronary Arteries)
A new prospective observational study of 38 patients suffering from myocardial infarction…
Corevalve Evolut R (Medtronic) and Edwards Sapien 3 (Edward Lifesciences) Valves Reveal Equivalence in Transcatheter Aortic Valve Implantation (TAVI) in a Head-to-Head Comparison
Results from an open-label, multi-center, 2x2 factorial design randomized trial powered for…
Polymer coated sustained-release Eluvia DES outshines non-polymer coated Zilver DES for femoropopliteal artery stenosis
A randomized global, prospective, multi-center, single-blind trial comparing the Eluvia paclitaxel-eluting stent…
Treating the culprit lesion associated with decreased mortality versus immediate multi-vessel PCI in cardiogenic shock
In a randomized multi-center clinical trial that enrolled more than 700 patients…