BETTER CARE-HF: EHR-embedded alert increased MRA prescription in AMBULATORY HFrEF patients
Key Points Many patients with heart failure with reduced ejection fraction (HFrEF)…
TAVR at 3 years showed durable benefits vs surgery: the Evolut Low Risk Trial
Key Points Both transcatheter aortic valve replacement (TAVR) and surgical aortic valve…
TRILUMINATE: Tri-Clip reduces tricuspid regurgitation and improves quality of life at one year
Key Points: There have been limited data examining the safety and efficacy…
FLAME: FlowTriever use for PE associated with decreased in-hospital adverse outcomes
Key Points: Mortality in high-risk PE remains unacceptably high (25%) despite advances…
Intravascular Imaging-Guiding PCI in Complex Coronary Lesions Linked to Better Outcomes: The RENOVATE-COMPLEX-PCI Study
Key Points: Intravascular imaging-guided PCI shows promise in improving outcomes for patients…
TARGET Trial: On-site CT-FFR Feasible and Effective in stable CAD
Key points: The TARGET trial is the first randomized trial designed to…
HALO – Baxdrostat Fails to Beat Placebo for Blood Pressure Reduction in Uncontrolled Hypertension
Key Points Baxdrostat, a highly selective aldosterone synthase inhibitor, reduced systolic blood…
Evolocumab Effect on Plaque Characteristics in Stable CAD Patients
Key Points The YELLOW III study aimed to assess the effect of…
No difference in Heart Failure Outcomes with Advanced Imaging modalities vs SPECT: The AIMI-HF Trial
Key Points: Imaging may be underused in patients with ischemic heart failure…
Viability Not Linked to Survival or LV improvement: The REVIVED-BCIS2 Randomized Trial
Key Points: -It is unclear whether myocardial viability tests should be used…
Atorvastatin Reduced Left Ventricular Dysfunction From Anthracyclines: The STOP-CA Trial
Key Points -Anthracycline therapy is associated with the development of heart…
CLEAR Outcomes – Bempedoic Acid reduces Cardiovascular Events among Statin-Intolerant Patients
Key Points Bempedoic acid, an ATP citrate lyase inhibitor, has been shown…
BrigHTN: Baxdrostat, an aldosterone synthase inhibitor, showed dose-related reductions in blood pressure and safely and effectively lowers blood pressure in patients with resistant hypertension
Key Points In a Phase 2 randomized trial, baxdrostat, a highly potent…
FRESH –First-in-Class Aminopeptidase-A Inhibitor Firibastat Fails in Resistant Hypertension
Key Points Hypertension remains a major public health threat contributing significantly to…
PRECISION –Dual Endothelin Receptor Antagonist Aprocitentan Superior to Placebo in Resistant Hypertension
Key Points Despite the many drug classes available to treat hypertension, the…
RAPID – Self-Administered Etripamil Improves PSVT Conversion to Sinus Rhythm
Key Points -The RAPID study achieved its primary efficacy endpoint of terminating…
NOVA – No significant difference in rate of post-op AF with botulinum toxin vs placebo
Key Points: -In a Phase II, dose-ranging trial of epicardial fat pad…
RIVARAD: Post-Procedural Rivaroxaban Use After Radial Access for Coronary Procedures Reduces Radial Artery Occlusion at 30 Days
Key Points: Radial artery occlusion (RAO) is the most common complication after…
EPIC-STEMI: Early Routine PCSK-9 Use Added to High Intensity Statin Reduces LDL after Primary PCI for STEMI
Key Points: Early high-intensity statin therapy is standard of practice in acute…
Extended outcomes of BEST: No difference in MACE between PCI and CABG in MVD at 12 years, but higher repeat revascularization and spontaneous MI in PCI arm
Key Points: Previous studies have demonstrated the superiority of CABG over PCI…