HOST-BR: 3 Months Of DAPT Might be Reasonable For Both Low- And High-Bleeding Risk Patients After PCI With DES
Key Points After DES placement, guidelines recommend considering shorter DAPT duration (e.g.…
SOUL: Oral Semaglutide Reduced CV Events In High-Risk Patients With T2DM with ASCVD or CKD
Key Points Injectable semaglutide, a GLP-1 receptor agonist, reduces CV events in…
Bentracimab Significantly Restored Platelet Function in Patients Taking Ticagrelor and Undergoing Urgent Surgery
Key Points: A major limitation of antithrombotic therapy is the risk of…
Semaglutide Increased Walking Distance in Patients with T2DM and Symptomatic PAD
Key Points: Patients with peripheral artery disease (PAD) in combination with type…
API-CAT Trial: Extended Reduced-Dose Apixaban Non-Inferior to Full Dose for VTE in Cancer
Key Points: Venous thromboembolism (VTE) is a leading cause of mortality in…
WARRIOR Trial: Intensive Medical Therapy Didn’t Lower Events in INOCA vs Usual Care
Key Points: In the WARRIOR trial, ~ 2500 women with signs and…
RIVAWAR Trial: Rivaroxaban Is Comparable to Warfarin for Post-MI Left Ventricular Thrombus
Key Points: Left ventricular thrombus (LVT) is a serious complication following heart…
Sodium Zirconium Cyclosilicate Enables MRA Optimization in HFrEF with Hyperkalemia: Insights from the REALIZE-K Trial
Key Points: REALIZE-K trial was a double-blind, placebo-controlled, randomized withdrawal study investigating…
Enhanced Efficiency and Accuracy in Echocardiographic Workflow: Insights from the AI-ECHO RCT
Key Points: AI-ECHO RCT is the first randomized trial to evaluate AI-based…
Obicetrapib Demonstrates Promising Lipid-Lowering Efficacy and Safety in Heterozygous Familial Hypercholesterolemia: BROOKLYN
Key Points: BROOKLYN was a phase III trial that assessed the safety…
Acoramidis: Open-Label Extension Data Confirms Sustained Benefits in Transthyretin Cardiac Amyloidosis
Key Points: Sustained Efficacy: Continued improvements in cardiac biomarkers, functional capacity, and…
Geographic Variations in Racial Disparities for Peripheral Artery Disease Treatment in the U.S.
Key Takeaways: Black patients with peripheral artery disease (PAD) had significantly higher…
Mitral Annular Calcification Severity Predicts Outcomes in Severe Aortic Stenosis Patients Undergoing TAVR
Key Points: The presence of mitral annular calcification (MAC) in prior studies…
Impact of Technology-Enabled Home-Based Cardiac Rehabilitation on Functional Status and Cardiovascular Health Metrics: mTECH-Rehab Trial
Key Points: Cardiac rehabilitation (CR) is a guideline-directed multifaceted intervention that is…
Zerlasiran Was Well Tolerated and Reduced Time-averaged Lp(a) Concentration: The ALPACAR Trial
Key Takeaways: Zerlasiran, a short interfering RNA (siRNA) targeting lipoprotein(a) (Lp(a)), was…
AMULET IDE Trial 5 years Showed Long-term Safety and Efficacy of AMPLATZER Amulet and Watchman Device in LAAO
Key Takeaways: The AMULET IDE trial compared the AMPLATZER Amulet occluder with…
ATTR-Specific Medication and AVR Improve Survival in Patients with Aortic Stenosis and ATTR Cardiac Amyloidosis
Key Takeaways: In this international registry, 266 patients with dual pathology, aortic…
Bempedoic Acid Reduces Major Adverse Limb Events in Patients with PAD : A Pre-specified Analysis from the CLEAR Outcomes Trial
Key Points: Patients with peripheral artery disease (PAD) at an increased risk…
Consistent Efficacy and Safety of Finerenone in Women and Men: A Secondary Analysis of the FINEARTS-HF Trial
KEY POINTS: Historically women have been underrepresented in cardiovascular clinical trials, however,…
Oral Muvalaplin Lowered Lipoprotein(a): The KRAKEN Trial
Key Takeaways: KRAKEN was an international, multicenter, placebo controlled, phase 2 trial…