IVUS-guided PCI was not Associated with Lower Risk of Target-Vessel Failure vs Angiography-guided PCI alone in High-risk Patients: OPTIMAL trial
Key Points • In the randomized OPTIMAL trial, IVUS-guided PCI did not…
Intensive Triglyceride Lowering with Olezarsen Does Not Reduce Coronary Plaque Progression in the Essence-TIMI 73b CCTA Sub Study
Key Points Triglyceride-rich lipoproteins (TRLs) and remnant cholesterol have been increasingly implicated…
Indigenous “Food is Medicine” Program Reduced Hospitalizations in Heart Failure Patients in MUTTON-HF Trial
Key Points Nutrition insecurity is a major driver of cardiovascular health disparities…
Retinal AI Scan Could Help Identify Individuals with Elevated ASCVD Risk
Key Points Cardiovascular prevention often breaks down before treatment ever begins. Many…
Mobile App–Based Sodium Reduction Strategy Did Not Improve SBP in LowSalt4Life 2 Trial
Key Points: Excess dietary sodium intake remains a major contributor to hypertension…
Electronic Clinician Notifications Improved Timely Valve Evaluation and Treatment in AS and MR: The ALERT Trial
Key Points Severe aortic stenosis and mitral regurgitation are common, effective valve…
ADAPT-CEC Trial: A Hybrid AI + Human Approach Proved Most Accurate
Key Points Behind every major cardiovascular trial is a less visible but…
Patient-Facing HeartLogic Alerts Lowered Hospitalizations in Heart Failure: The NOTIFY-HF Trial
Key Points Heart failure can worsen long before patients feel it. The…
Enlicitide Shows Durable LDL-C Lowering Through 52 Weeks in CORALreef On-Treatment Analysis
Key Points LDL lowering is only as good as its power to…
Full-Body Embolic Protection With Emboliner Non-inferior to Sentinel With Superior Debris Capture During TAVR: PROTECT H2H Trial
Key Points Embolic complications remain a key concern during transcatheter aortic valve…
Deferral of PCI Non-inferior to Routine Revascularization Before TAVI in Patients with CAD: PRO-TAVI Trial
Key Points Coronary artery disease (CAD) is present in approximately half of…
SURVIV: Transcatheter Mitral Valve-in-Valve Is Superior to Redo Surgery for Failed Mitral Bioprostheses at 1 Year
Key Points: The use of bioprosthetic mitral valve replacement has increased substantially…
Lung Impedance–Guided Therapy Reduces Hospitalizations and Mortality in HFpEF: Results from the IMPEDANCE-HFpEF Trial
Key Points: Patients with heart failure with preserved ejection fraction (HFpEF) are…
SirPAD Finds Sirolimus-Coated Balloon Angioplasty Reduced Major Adverse Limb Events in Infrainguinal PAD
Key Points • In the randomized SirPAD trial, sirolimus-coated balloon angioplasty was…
Angiography-Derived FFR Noninferior to Pressure-Wire Guidance for PCI Decision-Making: ALL-RISE Trial
Key Points Physiologic lesion assessment using fractional flow reserve (FFR) is a…
Elective Left Ventricular Unloading Does Not Improve Outcomes in High-Risk PCI: CHIP-BCIS3 Trial
Key Points Complex PCI in patients with severe left ventricular dysfunction remains…
Less Invasive FFR Comparable to FFR: Results from FAST III trial
Key Points • In the FAST III trial, a vFFR guided revascularization…
2-Year Follow up of TRI-FR Trial: TEER Reduced HF Events in Severe Isolated Tricuspid Regurgitation
Key Points • In the extended 2 year follow up of the…
MOMENTUM: Hypercortisolism Highly Prevalent Among Patients With Resistant Hypertension
Key Points: Resistant hypertension (rHTN), defined as blood pressure remaining above goal…
HOST-EXAM 10-Year Follow-Up: Clopidogrel Monotherapy Associated With Lower Rate of Primary Composite Endpoint vs Aspirin After PCI
Key Points: Antiplatelet monotherapy is a cornerstone of secondary prevention after PCI…