SOLVE-TAVI Trial: No Difference in 30-Day Outcomes Between Balloon-Expandable and Self-Expandable Aortic Valves in High Risk Patients With Symptomatic Aortic Stenosis
A trial led by Dr. Holger Thiele showed that there was no difference in outcomes by 30 days when comparing the use of self-expandable and balloon-expandable valves in transcatheter aortic…
1K Plaque Associated With Lower Future ACS Risk: Case Control Cohort Study (Analysis from ICONIC Study)
In an original investigation by Dr. Alexander R. van Rosendael et al recently published in JAMA Cardiology, it was found that the higher-density calcified plaque, referred to as 1K plaque…
Study Shows Pre-Dilation Associated with Worse Outcomes As Compared to Direct Stenting of Saphenous Vein Graft Lesions in Patients Undergoing PCI
A post-hoc analysis of the Drug-Eluting Stents Versus Bare-Metal Stents in Saphenous Vein Graft Angioplasty (DIVA) trial was recently published in Circulation: Cardiovascular Interventions. The study led by Dr. Faisal…
Trial Showed Implementation of High Sensitivity Cardiac Troponin Assays and Universal Definition of Myocardial Infarction Recommendations in Patients with Suspected Acute Coronary Syndrome Increased Diagnosis Rate Without a Change in Outcomes
A recent study by Dr. Chapman, published in Circulation, showed that implementation of high sensitivity cardiac troponin (hs-cTn) and the fourth universal definition of myocardial infarction (MI) increased the identification…
Population-Based Cohort Study Shows Blood Pressure Trajectories Over The Life Course Progress More Rapidly in Women Compared to Men
A new study by Dr. Hongwei, published in JAMA Cardiology, demonstrated that blood pressure (BP) trajectories over the life course progress more rapidly in women compared to men, a process…
HDL Dysfunction Is Associated With an Increased Risk of Acute Coronary Syndrome
Maria Trinidad Soria-Florido et al. published the results of their study on high-density lipoprotein (HDL) function and coronary syndrome in Circulation. They showed that low amount of HDL sphingosine-1-phosphate (S1P)…
Study Shows Hepatitis C Status Not Associated With Adverse Events in Adult Heart Transplant Patients by 1 Year
A recent study by Dr. Kilic, published in the American Heart Association Journal, showed similar adverse outcomes in the 1-year survival, rejection rates, and complications of patients who received a…
Study Shows Abnormalities in Both Systolic and Diastolic Echocardiographic Features Associated with Mortality in Patients with Cardiac Amyloidosis
A study published by Dr. Liza Chacho published in the European Heart Journal showed that in patients with three distinct genotypes of transthyretin cardiomyopathy, both diastolic and systolic echocardiographic parameters…
Randomized Trial Shows Prasugrel Associated with Better Endothelial Function and Stronger Platelet Inhibition as Compared to Clopidogrel or Ticagrelor in Patients with ACS Who Undergo Stenting
In a recent randomized, three-arm, parallel, blinded study by Dr. Schnorbus, published in European Heart Journal, prasugrel was associated with improved endothelial function, more potent platelet inhibition, and decreased plasma…
Trial Shows OCT Does Not Reduce Incidence of Non-optimal Deployment of Bioresorbable Vascular Scaffold as Compared to Standard Angiography
A randomized controlled trial led by Dr. Seung-Yul Lee published in Circulation: Cardiovascular Intervention showed that in patients who required percutaneous coronary intervention, the use of optical coherence tomography (OCT)…
Type 2 Myocardial Infarction (T2MI) Is Associated With Higher All-Cause Mortality Compared to Type 1 Myocardial Infarction (T1MI)
Raphael et al. showed in a prospective cohort study, published in Circulation, that type 2 myocardial infarction (T2MI), defined as an acute imbalance between oxygen delivery to the myocardium and…
Trial Shows Abstinence From Alcohol Can Reduce Recurrence of Atrial Fibrillation In Patients With Paroxysmal Atrial Fibrillation Who Regularly Consume Alcohol
In an original study conducted by Dr. Aleksandr Voskoboinik et al. recently published in The New England Journal of Medicine, it was found that alcohol consumption is a modifiable risk…
Elevated Coronary Sinus Neuropeptide Y Levels Are Associated With Adverse Outcomes in Patients With Chronic Heart Failure
The study by Dr. Ajijola, published in JAMA Cardiology, found that elevated coronary sinus neuropeptide Y (NPY) level is associated with adverse cardiovascular events in stable patients with chronic heart…
KCEA-APO(a)-LRx Trial: Anti-sense Oligonucleotide Shows Promise in Reducing Blood Lipoprotein(a) Levels in Patients With Established Cardiovascular Disease
A study led by Dr. Sotirios Tsimikas published in the New England Journal of Medicine showed that the hepatocyte-directed antisense oligonucleotide APO(a)-LRx significantly reduced the blood lipoprotein(a) levels in patients…
Left Ventricular Myocardial Stiffness, an Early Sign of Stage B HFpEF, Is Observed in Patients With Left Ventricular Hypertrophy and Elevated Cardiac Biomarkers
A study led by Dr. Michinari Hieda published in Circulation showed that left ventricular myocardial stiffness is greater in patients with left ventricular hypertrophy and elevated cardiac biomarkers as compared…
Study Shows Heart Transplants From Hepatitis C Positive Donors Safe; Potential for Expanding Donor Pool and Shortening Wait-Times
In an observational case series of 80 patients who underwent heart transplant using hearts from hepatitis C (HCV)–positive donors, it has been shown that short-term (30-day) and long-term survival (1-year)…
The Sarcomeric Human Cardiomyopathy Registry: Race Associated with Disease Expression and Clinical Outcomes Among Patients with Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is the most common inherited genetic disorder of the myocardium, and the number one culprit of sudden cardiac death in athletes, particularly African Americans. "Is race associated…
SYNTAX III REVOLUTION Trial: Non-invasive CT Scanning as a Potential Alternative to Invasive Coronary Angiography for Treatment Decision-Making in Patients with Complex Coronary Artery Disease
A cross-sectional observational study enrolling 223 patients with 3-vessel coronary artery disease, has shown that compared to conventional invasive coronary angiography, a noninvasive physiology assessment using fractional flow reserve CT…
Persistently Elevated Neuropeptide Y, a Sympathetic Neurotransmitter, is Found to be Associated with Ventricular Arrhythmias in Patients with Myocardial Infarction
The sympathetic drive leading to the release of arrhythmogenic agents after myocardial infarction (MI) is the target of pharmacologic treatment to reduce the mortality associated with post-MI arrhythmias. Beta-blockers, so…
385,000 Patient Study Shows Poor Sleep Behavior Associated With Increased Risk of Coronary Heart Disease and Stroke
A study led by Dr. Mengyu Fan published in the European Heart Journal showed that a healthy sleep pattern was associated with a lower risk of cardiovascular disease (CVD), congestive…