Mouse Study Shows High Saturated Fat Diet May Promote Arrhythmias By Activating NADPH Oxidase 2
In an original article written by Leroy C. Joseph et al, it was found the molecular mechanisms of cardiac metabolism to arrhythmia and NAPDH Oxidase2(NOX2) deletion or pharmacological inhibition can…
Study Demonstrates Decreasing Medical Therapy Utilization Among Veteran Patients Treated with PCI Over 5 Years
11/6/2019- Joe X. Xie et. al recently published the results of a Veterans cohort study in Circulation. They were able to show a meaningful decline in the rate of important…
Registry Data Demonstrates No Difference in Survival Between Extracorporeal CPR and Conventional CPR in Patients With Out of Hospital Cardiac Arrest
A study led by Dr. Wulfran Bougouin published in the European Heart Journal analyzed out of hospital cardiac arrests (OHCA) and compared outcomes in patients who received and did not…
Blinded Post-PCI Physiologic Assessment Detected Residual Ischemia After Angiographically Successful Result
The result of a study, presented at ACC 2019 in March, 2019 and recently published in JACC Interventional Cardiology, showed that despite angiographically successful percutaneous coronary intervention (PCI), physiological assessment…
20,000 Patient Randomized Trial Shows Ingestion of Anti-hypertensive Medication at Night Associated with Better Blood Pressure Control and Improved Cardiovascular Outcomes
A randomized trial, led by Dr. Ramon Hermida, revealed that the routine ingestion of at least one prescribed anti-hypertensive medication in patients with hypertension led to improved control of ambulatory…
Cardiac Rehabilitation Is Associated With Decreased Hospitalization and Mortality After Cardiac Valve Surgery
Cardiac rehabilitation after cardiac valve surgery is associated with lower hospitalizations and mortality at one year. A recent cohort study of Medicare beneficiaries, published in JAMA Cardiology, revealed.
Treatment with Statins, RAAS Inhibitors and Platelet Inhibitors After CABG is Essential, While the Use of Beta-blockers is Questionable: Swedish Study
In a recent study published in the European Heart Journal, Erik Björklund et al. found that the secondary prevention medications, such as statins and renin-angiotensin-aldosterone system (RAAS) inhibitors, and platelet…
New-Onset AF After TAVR linked To Worse Long-Term Outcomes Compared With Patients With Pre-Existing AF and No AF
A registry-based cohort study including 72,660 Medicare patients with and without atrial fibrillation (AF) who underwent non-apical transcatheter aortic valve replacement (TAVR) from 2014 to 2016, has shown that, TAVR…
20-Year Study Shows Statin Use Associated with Reduced Cardiovascular Event Rate in Children with Familial Hypercholesterolemia
A study led by Dr. Ilse Luirink published in the New England Journal of Medicine showed that initiating statins in children with familial hypercholesterolemia slowed the progression of carotid intima-media…
THEMIS Study: Ticagrelor Plus Aspirin Associated with Lower Ischemic Event Rate but Higher Bleeding Rate Than Aspirin Alone in Patients with Diabetes and Stable Coronary Artery Disease
Use of ticagrelor plus aspirin in patients with stable coronary artery disease and type 2 diabetes significantly lowers the risk of major adverse cardiovascular events compared with aspirin alone, but…
11-Year Follow-Up Study Shows Drug Eluting Devices Safe in Patients with Peripheral Vascular Disease
The results of a real-world safety analysis showed that over a follow-up period of up to 11 years, there was no evidence of increased mortality in patients who underwent endovascular…
17 Year Study Shows Changes in Income Can Influence the Occurrence of Cardiovascular Disease
A study led by Mr. Stephen Wang, published in JAMA Cardiology, showed that an income drop over 6 years was associated with an increased incidence of cardiovascular disease over the…
ORION-1: 1-Year Follow-Up Data Affirms 2-dose Regimen Using 300 mg of Inclisiran For Persistent LDL-C Lowering
A randomized, double blind, placebo-controlled, phase II clinical trial studying the effect of a novel protein proprotein convertase subtilisin/kexin type 9 (PCSK9) synthesis inhibitor (inclisiran) on serum low density lipoprotein…
New 21,000 PCI Study Shows Same-Day Discharge Associated with Reduced Costs But No Difference in Mortality or Readmission Rates in Patients Undergoing Elective PCI
A study led by Dr. Jennifer Rymer published in the American Heart Journal suggested that same-day discharge after an elective percutaneous coronary intervention (PCI) is being increasingly adopted and is…
COAPT: Transcatheter Mitral Valve Repair Is a Cost Effective Treatment In Patients with Heart Failure and Secondary Mitral Valve Regurgitation
New findings from the COAPT study were just published in Circulation and presented at TCT 2019 by Dr. Suzanne J. Baron. The findings of the study suggest that in patients…
PARTNER 3: TAVR Associated with Better Health Status At 12 Months As Compared to SAVR in Patients with Severe Aortic Stenosis and Low Surgical Risk
Findings from the ongoing PARTNER 3 trial were published in the Journal of the American College of Cardiology and presented at TCT 2019 by Dr. Suzanne J. Baron. The findings…
REMEDIAL III: Urine Flow Rate Guided Hydration Is Superior to Left Ventricular End‐Diastolic Pressure Guided Hydration for Preventing Renal And/Or Pulmonary Edema in Interventional Cardiology
Findings of an ongoing REMEDIAL (REnal Insufficiency Following Contrast MEDIA Administration triaL) III trial have been published recently in Catheter Cardiovasc Interventions and were presented by Dr. Carlo Briguori from…
EXCEL Trial: Five-Year Data Suggests PCI Non-Inferior to CABG in Patients with Left Main Coronary Artery Disease
The results of a randomized controlled trial led by Dr. Gregg W. Stone presented at TCT 2019 and published in the New England Journal of Medicine showed that in patients…
The COMPLETE Timing Substudy: A Randomized Trial of Complete Staged Revascularization Vs. Infarct Artery PCI Alone in Patients With Acute Myocardial Infarction and Multivessel Disease – Importance of Revascularization Timing
The results of a substudy of the COMPLETE Trial were presented at TCT 2019 by Dr. David Wood, an interventional cardiologist, and Professor of Medicine at the University of British…
AUGUSTUS Trial: Dual Therapy with P2Y12 Inhibitor and Apixaban Safer Than Triple Therapy or Dual Therapy with Warfarin in Patients with Atrial Fibrillation and Acute Coronary Syndrome or Percutaneous Coronary Intervention
The results of a randomized controlled trial led by Dr. Renato Lopes presented at TCT 2019 and published in the New England Journal of Medicine showed that in patients with…